2. Others
  3. Isotope-Labeled Compounds
  4. Linoleic acid-d5

Linoleic Acid-d5 is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism.

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Linoleic acid-d<sub>5</sub> Chemical Structure

Linoleic acid-d5 Chemical Structure

CAS No. : 1169764-58-2

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Other Forms of Linoleic acid-d5:

Linoleic acid-d5 Related Antibodies

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Description

Linoleic Acid-d5 is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Linoleic acid-d5 Related Antibodies
Molecular Weight

285.48

Formula

C18H27D5O2
CAS No.
Unlabeled CAS

60-33-3
Appearance

Liquid

Color

Colorless to light yellow

SMILES

O=C(O)CCCCCCC/C=C\C/C=C\CCCC([2H])([2H])C([2H])([2H])[2H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Solution, -20°C, 2 years
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (350.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

0.1 M NaOH : 8.33 mg/mL (29.18 mM; ultrasonic and warming and adjust pH to 11 with NaOH and heat to 60°C)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

COA (239 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
0.1 M NaOH / DMSO 1 mM 3.5029 mL 17.5144 mL 35.0287 mL 87.5718 mL
5 mM 0.7006 mL 3.5029 mL 7.0057 mL 17.5144 mL
10 mM 0.3503 mL 1.7514 mL 3.5029 mL 8.7572 mL
15 mM 0.2335 mL 1.1676 mL 2.3352 mL 5.8381 mL
20 mM 0.1751 mL 0.8757 mL 1.7514 mL 4.3786 mL
25 mM 0.1401 mL 0.7006 mL 1.4011 mL 3.5029 mL
DMSO 30 mM 0.1168 mL 0.5838 mL 1.1676 mL 2.9191 mL
40 mM 0.0876 mL 0.4379 mL 0.8757 mL 2.1893 mL
50 mM 0.0701 mL 0.3503 mL 0.7006 mL 1.7514 mL
60 mM 0.0584 mL 0.2919 mL 0.5838 mL 1.4595 mL
80 mM 0.0438 mL 0.2189 mL 0.4379 mL 1.0946 mL
100 mM 0.0350 mL 0.1751 mL 0.3503 mL 0.8757 mL
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Linoleic acid-d5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Linoleic acid-d51169764-58-2Isotope-Labeled CompoundsInhibitorinhibitorinhibit

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