1. GPCR/G Protein Neuronal Signaling Autophagy
  2. Opioid Receptor Autophagy
  3. Loperamide-d6 hydrochloride

Loperamide-d6 hydrochloride  (Synonyms: R-18553-d6 hydrochloride)

Cat. No.: HY-B0418AS Purity: 99.07%
COA Handling Instructions

Loperamide-d6 (hydrochloride) is a deuterium labeled Loperamide hydrochloride. Loperamide hydrochloride is an opioid receptor agonist for the treatment of diarrhea[1].

For research use only. We do not sell to patients.

Loperamide-d<sub>6</sub> hydrochloride Chemical Structure

Loperamide-d6 hydrochloride Chemical Structure

CAS No. : 1189469-46-2

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1 mg USD 680 In-stock
5 mg USD 1850 Get quote
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50 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Loperamide-d6 (hydrochloride) is a deuterium labeled Loperamide hydrochloride. Loperamide hydrochloride is an opioid receptor agonist for the treatment of diarrhea[1].

Molecular Weight

519.54

Formula

C29H28D6Cl2N2O2

CAS No.
Unlabeled CAS

34552-83-5

Appearance

Solid

Color

White to off-white

SMILES

Cl[H].O=C(N(C([2H])([2H])[2H])C([2H])([2H])[2H])C(C1=CC=CC=C1)(C2=CC=CC=C2)CCN3CCC(O)(C4=CC=C(Cl)C=C4)CC3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (96.24 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 1 mg/mL (1.92 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9248 mL 9.6239 mL 19.2478 mL
5 mM 0.3850 mL 1.9248 mL 3.8496 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 1.9248 mL 9.6239 mL 19.2478 mL 48.1195 mL
DMSO 5 mM 0.3850 mL 1.9248 mL 3.8496 mL 9.6239 mL
10 mM 0.1925 mL 0.9624 mL 1.9248 mL 4.8119 mL
15 mM 0.1283 mL 0.6416 mL 1.2832 mL 3.2080 mL
20 mM 0.0962 mL 0.4812 mL 0.9624 mL 2.4060 mL
25 mM 0.0770 mL 0.3850 mL 0.7699 mL 1.9248 mL
30 mM 0.0642 mL 0.3208 mL 0.6416 mL 1.6040 mL
40 mM 0.0481 mL 0.2406 mL 0.4812 mL 1.2030 mL
50 mM 0.0385 mL 0.1925 mL 0.3850 mL 0.9624 mL
60 mM 0.0321 mL 0.1604 mL 0.3208 mL 0.8020 mL
80 mM 0.0241 mL 0.1203 mL 0.2406 mL 0.6015 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Loperamide-d6 hydrochloride
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