1. Apoptosis
  2. c-Myc
  3. Lusianthridin

Lusianthridin, a pure compound from Dendrobium venustum, have an anti-migratory effect. Lusianthridin enhances c-Myc degradation through the inhibition of Src-STAT3 signaling.

For research use only. We do not sell to patients.

Lusianthridin Chemical Structure

Lusianthridin Chemical Structure

CAS No. : 87530-30-1

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Based on 1 publication(s) in Google Scholar

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Description

Lusianthridin, a pure compound from Dendrobium venustum, have an anti-migratory effect. Lusianthridin enhances c-Myc degradation through the inhibition of Src-STAT3 signaling[1].

In Vitro

Lusianthridin (0-100 μM) inhibits cell viability at concentrations greater than 50 μM in both H460 and H292 cells[1].
Lusianthridin significantly reduces the CSC populations in both H460 and H292 cells of the CSC spheres, with a significant decrease in the size of the H460 CSC spheres by approximately 10%, 63%, and 77% at day 3 at concentration 5, 10, and 20 μM Lusianthridin, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: The human non-small cell lung cancer cell lines, NCI-H460, and NCI-H292 cells[1]. 0-100 μM.
Concentration: 0-100 μM.
Incubation Time: 24 h.
Result: Caused a significant reduction in terms of cell viability at concentrations greater than 50 μM in both H460 and H292 cells.
Molecular Weight

242.27

Formula

C15H14O3

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC(C=C1CC2)=CC=C1C3=C2C=C(OC)C=C3O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation

Purity: ≥98.0%

References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Lusianthridin
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HY-121418
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