2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. Mal-PEG2-Val-Cit-PABA-PNP

Mal-PEG2-Val-Cit-PABA-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

Mal-PEG2-Val-Cit-PABA-PNP Chemical Structure

Mal-PEG2-Val-Cit-PABA-PNP Chemical Structure

CAS No. : 1345681-52-8

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Based on 1 publication(s) in Google Scholar

Mal-PEG2-Val-Cit-PABA-PNP Related Antibodies

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Description

Mal-PEG2-Val-Cit-PABA-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Protease Cleavable Linker

 

Cleavable Linker

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Mal-PEG2-Val-Cit-PABA-PNP Related Antibodies
Molecular Weight

755.73

Formula

C34H41N7O13
CAS No.
Unlabeled Cas

Appearance

Solid

Color

White to off-white

SMILES

O=C(OC1=CC=C(C=C1)[N+]([O-])=O)OCC(C=C2)=CC=C2NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(OCCOCCN3C(C=CC3=O)=O)=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Purity & Documentation
References
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Mal-PEG2-Val-Cit-PABA-PNP Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mal-PEG2-Val-Cit-PABA-PNP1345681-52-8ADC LinkerAntibody-drug conjugates linkercleavableADCPEGInhibitorinhibitorinhibit

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Mal-PEG2-Val-Cit-PABA-PNP
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HY-131156
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