1. GPCR/G Protein Immunology/Inflammation
  2. CCR
  3. Met-RANTES (human)

Met-RANTES (human)  (Synonyms: MSPYSSDTTPCCFAYIARPLPRAHIKEYFYTSGKCSN)

Cat. No.: HY-P4191
Handling Instructions

Met-RANTES (human) is a partial antagonist of CCR5. Met-RANTES (human) reduces the infiltration of blood monocytes into the liver.

For research use only. We do not sell to patients.

Met-RANTES (human) Chemical Structure

Met-RANTES (human) Chemical Structure

CAS No. : 1883816-50-9

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Description

Met-RANTES (human) is a partial antagonist of CCR5. Met-RANTES (human) reduces the infiltration of blood monocytes into the liver[1].

Molecular Weight

7972.90

Formula

C355H543N97O101S6

CAS No.
Unlabeled CAS

Sequence

Met-Ser-Pro-Tyr-Ser-Ser-Asp-Thr-Thr-Pro-Cys-Cys-Phe-Ala-Tyr-Ile-Ala-Arg-Pro-Leu-Pro-Arg-Ala-His-Ile-Lys-Glu-Tyr-Phe-Tyr-Thr-Ser-Gly-Lys-Cys-Ser-Asn-Pro-Ala-Val-Val-Phe-Val-Thr-Arg-Lys-Asn-Arg-Gln-Val-Cys-Ala-Asn-Pro-Glu-Lys-Lys-Trp-Val-Arg-Glu-Tyr-Ile-Asn-Ser-Leu-Glu-Met-Ser (Disulfide bridge: Cys11-Cys35, Cys12-Cys51)

Sequence Shortening

MSPYSSDTTPCCFAYIARPLPRAHIKEYFYTSGKCSNPAVVFVTRKNRQVCANPEKKWVREYINSLEMS (Disulfide bridge: Cys11-Cys35, Cys12-Cys51)

SMILES

O=C([C@@H](N)CCSC)N[C@H](C(N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N3[C@H](C(N[C@H](C(N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H]5CCCCN)=O)=O)CO)=O)[C@@H](C)O)=O)CC6=CC=C(O)C=C6)=O)CC7=CC=CC=C7)=O)CC8=CC=C(O)C=C8)=O)CCC(O)=O)=O)CCCCN)=O)[C@H](CC)C)=O)CC9=CNC=N9)=O)C)=O)CCCNC(N)=N)=O)CCC4)=O)CC(C)C)=O)CCC3)=O)CCCNC(N)=N)=O)C)=O)[C@H](CC)C)=O)CC%10=CC=C(O)C=C%10)=O)C)=O)CC%11=CC=CC=C%11)=O)CSSC[C@H](NC%12=O)C(N[C@H](C(N[C@H](C(N%13[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CO)=O)CCSC)=O)CCC(O)=O)=O)CC(C)C)=O)CO)=O)CC(N)=O)=O)[C@H](CC)C)=O)CC%14=CC=C(O)C=C%14)=O)CCC(O)=O)=O)CCCNC(N)=N)=O)C(C)C)=O)CC%15=CNC%16=CC=CC=C%15%16)=O)CCCCN)=O)CCCCN)=O)CCC(O)=O)=O)CCC%13)=O)CC(N)=O)=O)C)=O)=O)CSSC[C@H](NC5=O)C(N[C@H](C(N[C@H](C(N%17[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]%12C(C)C)=O)CCC(N)=O)=O)CCCNC(N)=N)=O)CC(N)=O)=O)CCCCN)=O)CCCNC(N)=N)=O)[C@@H](C)O)=O)C(C)C)=O)CC%18=CC=CC=C%18)=O)C(C)C)=O)C(C)C)=O)C)=O)CCC%17)=O)CC(N)=O)=O)CO)=O)=O)CCC2)=O)[C@@H](C)O)=O)[C@@H](C)O)=O)CC(O)=O)=O)CO)=O)CO)=O)CC%19=CC=C(O)C=C%19)=O)CCC1)=O)CO

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Met-RANTES (human)
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