2. Metabolic Enzyme/Protease
  3. Thrombin
  4. Metolazone-d7

Metolazone-d7  (Synonyms: SR-720-22-d7)

Cat. No.: HY-B0209S Purity: 99.90%
COA Handling Instructions

Molarity Calculator

Metolazone-d7 is deuterium labeled Metolazone. Metolazone (SR-720-22) is primarily used to treat congestive heart failure and high blood pressure.

For research use only. We do not sell to patients.

Metolazone-d<sub>7</sub> Chemical Structure

Metolazone-d7 Chemical Structure

CAS No. : 2714484-71-4

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1 mg USD 500 In-stock
5 mg USD 1000 In-stock
10 mg USD 1600 In-stock
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100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Other Forms of Metolazone-d7:

Metolazone-d7 Related Antibodies

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  • Biological Activity

  • Purity & Documentation

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Description

Metolazone-d7 is deuterium labeled Metolazone. Metolazone (SR-720-22) is primarily used to treat congestive heart failure and high blood pressure.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Metolazone-d7 Related Antibodies
Molecular Weight

372.88

Formula

C16H9D7ClN3O3S
CAS No.
Unlabeled Cas

17560-51-9
Appearance

Solid

Color

White to off-white

SMILES

O=S(C1=CC2=C(NC(C)N(C3=C([2H])C([2H])=C([2H])C([2H])=C3C([2H])([2H])[2H])C2=O)C=C1Cl)(N)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (268.18 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 0.67 mg/mL (1.80 mM; Need ultrasonic)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6818 mL 13.4091 mL 26.8183 mL
5 mM 0.5364 mL 2.6818 mL 5.3637 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 2.6818 mL 13.4091 mL 26.8183 mL 67.0457 mL
DMSO 5 mM 0.5364 mL 2.6818 mL 5.3637 mL 13.4091 mL
10 mM 0.2682 mL 1.3409 mL 2.6818 mL 6.7046 mL
15 mM 0.1788 mL 0.8939 mL 1.7879 mL 4.4697 mL
20 mM 0.1341 mL 0.6705 mL 1.3409 mL 3.3523 mL
25 mM 0.1073 mL 0.5364 mL 1.0727 mL 2.6818 mL
30 mM 0.0894 mL 0.4470 mL 0.8939 mL 2.2349 mL
40 mM 0.0670 mL 0.3352 mL 0.6705 mL 1.6761 mL
50 mM 0.0536 mL 0.2682 mL 0.5364 mL 1.3409 mL
60 mM 0.0447 mL 0.2235 mL 0.4470 mL 1.1174 mL
80 mM 0.0335 mL 0.1676 mL 0.3352 mL 0.8381 mL
100 mM 0.0268 mL 0.1341 mL 0.2682 mL 0.6705 mL
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Metolazone-d7 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Metolazone-d72714484-71-4SR-720-22-d7ThrombinInhibitorinhibitorinhibit

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