2. GPCR/G Protein Neuronal Signaling
  3. Dopamine Receptor
  4. MLS1082

MLS1082 is a pyrimidone-based D1-like dopamine receptor positive allosteric modulator, with an EC50 of 123 nM for DA-stimulated G protein signaling.

For research use only. We do not sell to patients.

MLS1082 Chemical Structure

MLS1082 Chemical Structure

CAS No. : 883958-36-9

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Based on 1 publication(s) in Google Scholar

MLS1082 Related Antibodies

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Description

MLS1082 is a pyrimidone-based D1-like dopamine receptor positive allosteric modulator, with an EC50 of 123 nM for DA-stimulated G protein signaling[1].

In Vitro

MLS1082 potentiate β-Arrestin- and G protein-Mediated D1R signaling[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

MLS1082 Related Antibodies
Molecular Weight

385.46

Formula

C24H23N3O2
CAS No.
Unlabeled CAS

Appearance

Solid

Color

White to off-white

SMILES

O=C1N(C2=CC=CC=C2)C(C3CCCCC3)=NC(N(C)C4=C5C=CC=C4)=C1C5=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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MLS1082 Related Classifications

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The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MLS1082883958-36-9MLS 1082MLS-1082Dopamine Receptorβ-ArrestinG-proteinD1RInhibitorinhibitorinhibit

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HY-123837
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