2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. EGFR
  4. MS154N

MS154N (compound 28) is the negative control of MS39 (HY-157581). MS39 is a potent and selective EGFR degrader. MS39 reduces the expression of EGFR and downstream signaling in HCC-827 and H3255 cells.

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MS154N Chemical Structure

MS154N Chemical Structure

CAS No. : 2675490-97-6

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MS154N Related Antibodies

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Description

MS154N (compound 28) is the negative control of MS39 (HY-157581). MS39 is a potent and selective EGFR degrader. MS39 reduces the expression of EGFR and downstream signaling in HCC-827 and H3255 cells[1].

Molecular Weight

915.45

Formula

C47H56ClFN8O8
CAS No.
Unlabeled CAS

SMILES

O=C1C2=C(C(N1C3C(N(C)C(CC3)=O)=O)=O)C(OCCCCCCCCNC(CCN4CCN(CCCOC5=CC6=C(NC7=CC=C(C(Cl)=C7)F)N=CN=C6C=C5OC)CC4)=O)=CC=C2
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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MS154N Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MS154N2675490-97-6EGFREpidermal growth factor receptorErbB-1HER1Epidermal Growth Factor ReceptorNSCLCMS39HCC-827H3255Inhibitorinhibitorinhibit

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MS154N
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HY-157579
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