N,N-Dimethylglycine-d₆ hydrochloride

Cat. No.: HY-W001158S Purity: ≥99.0%: FAQs
Data Sheet SDS COA Handling Instructions

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N,N-Dimethylglycine-d₆ (hydrochloride) is the deuterium labeled N,N-Dimethylglycine[1].

For research use only. We do not sell to patients.

N,N-Dimethylglycine-d<sub>6</sub> hydrochloride Chemical Structure

N,N-Dimethylglycine-d₆ hydrochloride Chemical Structure

CAS No. : 347840-03-3

Size	Price	Stock	Quantity
1 mg	USD 110	In-stock	Estimated Time of Arrival: December 31
5 mg		Get quote
10 mg		Get quote

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Other Forms of N,N-Dimethylglycine-d₆ hydrochloride:

N,N-Dimethylglycine hydrochloride In-stock

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Purity & Documentation
References
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Description

N,N-Dimethylglycine-d₆ (hydrochloride) is the deuterium labeled N,N-Dimethylglycine[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

145.62

Formula

C₄H₄D₆ClNO₂

CAS No.

347840-03-3

Unlabeled CAS

2491-06-7

Appearance

Solid

Color

White to off-white

SMILES

OC(CN(C([2H])([2H])[2H])C([2H])([2H])[2H])=O.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : ≥ 10 mg/mL (68.67 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

PBS (pH 7.2) : ≥ 10 mg/mL (68.67 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.8672 mL	34.3359 mL	68.6719 mL
5 mM	1.3734 mL	6.8672 mL	13.7344 mL
10 mM	0.6867 mL	3.4336 mL	6.8672 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥99.0%

Select Batch:

Data Sheet (270 KB) SDS (393 KB)

COA (249 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / PBS (pH 7.2)	1 mM	6.8672 mL	34.3359 mL	68.6719 mL	171.6797 mL
	5 mM	1.3734 mL	6.8672 mL	13.7344 mL	34.3359 mL
	10 mM	0.6867 mL	3.4336 mL	6.8672 mL	17.1680 mL
	15 mM	0.4578 mL	2.2891 mL	4.5781 mL	11.4453 mL
	20 mM	0.3434 mL	1.7168 mL	3.4336 mL	8.5840 mL
	25 mM	0.2747 mL	1.3734 mL	2.7469 mL	6.8672 mL
	30 mM	0.2289 mL	1.1445 mL	2.2891 mL	5.7227 mL
	40 mM	0.1717 mL	0.8584 mL	1.7168 mL	4.2920 mL
	50 mM	0.1373 mL	0.6867 mL	1.3734 mL	3.4336 mL
	60 mM	0.1145 mL	0.5723 mL	1.1445 mL	2.8613 mL