2. Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  3. DNA/RNA Synthesis Endogenous Metabolite
  4. N2-Acetylguanine

N2-Acetylguanine is a C2-modified guanine. N2-Acetylguanine binds GR (guanine-guanine riboswitch) with an Kd value of 300 nM. N2-Acetylguanine modulate transcriptional termination. N2-Acetylguanine has the potential for the research of antimicrobial agent.

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N2-Acetylguanine Chemical Structure

N2-Acetylguanine Chemical Structure

CAS No. : 19962-37-9

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Based on 1 publication(s) in Google Scholar

N2-Acetylguanine Related Antibodies

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Description

N2-Acetylguanine is a C2-modified guanine. N2-Acetylguanine binds GR (guanine-guanine riboswitch) with an Kd value of 300 nM. N2-Acetylguanine modulate transcriptional termination. N2-Acetylguanine has the potential for the research of antimicrobial agent[1].

In Vitro

N2-Acetylguanine completely disrupt a key Watson–Crick pairing interaction between the ligand and RNA[1].
N2-Acetylguanine (20 µM) promotes transcriptional termination in Bacillus subtilis [1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

N2-Acetylguanine Related Antibodies
Molecular Weight

193.16

Formula

C7H7N5O2
CAS No.
Unlabeled CAS

Appearance

Solid

Color

White to off-white

SMILES

O=C1N=C(NC2=C1NC=N2)NC(C)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 3.57 mg/mL (18.48 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.1771 mL 25.8853 mL 51.7706 mL
5 mM 1.0354 mL 5.1771 mL 10.3541 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.1771 mL 25.8853 mL 51.7706 mL 129.4264 mL
5 mM 1.0354 mL 5.1771 mL 10.3541 mL 25.8853 mL
10 mM 0.5177 mL 2.5885 mL 5.1771 mL 12.9426 mL
15 mM 0.3451 mL 1.7257 mL 3.4514 mL 8.6284 mL
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N2-Acetylguanine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N2-Acetylguanine19962-37-9DNA/RNA SynthesisEndogenous MetaboliteGRbacillus subtilisInhibitorinhibitorinhibit

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