2. Autophagy Metabolic Enzyme/Protease
  3. Autophagy Endogenous Metabolite
  4. Niacin-13C6

Niacin-13C6  (Synonyms: Nicotinic acid-13C6; Vitamin B3-13C6)

Cat. No.: HY-B0143S3 Purity: ≥98.0%
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Niacin-13C6 is the 13C-labeled Niacin. Niacin (Nicotinic acid) is a vitamin and is part of the vitamin B group.

For research use only. We do not sell to patients.

Niacin-<sup>13</sup>C<sub>6</sub> Chemical Structure

Niacin-13C6 Chemical Structure

CAS No. : 1189954-79-7

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Based on 1 publication(s) in Google Scholar

Other Forms of Niacin-13C6:

Niacin-13C6 Related Antibodies

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Description

Niacin-13C6 is the 13C-labeled Niacin. Niacin (Nicotinic acid) is a vitamin and is part of the vitamin B group.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Niacin-13C6 Related Antibodies
Molecular Weight

129.07

Formula

13C6H5NO2
CAS No.
Unlabeled CAS

59-67-6
Appearance

Solid

Color

White to off-white

SMILES

O=[13C]([13C]1=[13CH][13CH]=[13CH]N=[13CH]1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (387.39 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 10 mg/mL (77.48 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.7477 mL 38.7387 mL 77.4773 mL
5 mM 1.5495 mL 7.7477 mL 15.4955 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

Dosing volume
(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

COA (248 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 7.7477 mL 38.7387 mL 77.4773 mL 193.6933 mL
5 mM 1.5495 mL 7.7477 mL 15.4955 mL 38.7387 mL
10 mM 0.7748 mL 3.8739 mL 7.7477 mL 19.3693 mL
15 mM 0.5165 mL 2.5826 mL 5.1652 mL 12.9129 mL
20 mM 0.3874 mL 1.9369 mL 3.8739 mL 9.6847 mL
25 mM 0.3099 mL 1.5495 mL 3.0991 mL 7.7477 mL
30 mM 0.2583 mL 1.2913 mL 2.5826 mL 6.4564 mL
40 mM 0.1937 mL 0.9685 mL 1.9369 mL 4.8423 mL
50 mM 0.1550 mL 0.7748 mL 1.5495 mL 3.8739 mL
60 mM 0.1291 mL 0.6456 mL 1.2913 mL 3.2282 mL
DMSO 80 mM 0.0968 mL 0.4842 mL 0.9685 mL 2.4212 mL
100 mM 0.0775 mL 0.3874 mL 0.7748 mL 1.9369 mL
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Niacin-13C6 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Niacin-13C61189954-79-7Nicotinic acid-13C6Vitamin B3-13C6AutophagyEndogenous MetaboliteInhibitorinhibitorinhibit

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