2. GPCR/G Protein Neuronal Signaling
  3. Neurokinin Receptor
  4. Nolpitantium

Nolpitantium (SR140333) is a potent, selective, competitive, non-peptide tachykinin NK1 receptor antagonist. Nolpitantium blocks the activation of rat thalamic neurons after nociceptive stimulation.

For research use only. We do not sell to patients.

Nolpitantium Chemical Structure

Nolpitantium Chemical Structure

CAS No. : 153050-21-6

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Based on 1 publication(s) in Google Scholar

Nolpitantium Related Antibodies

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Description

Nolpitantium (SR140333) is a potent, selective, competitive, non-peptide tachykinin NK1 receptor antagonist. Nolpitantium blocks the activation of rat thalamic neurons after nociceptive stimulation[1].

IC50 & Target

NK1

 

Clinical Trial
Molecular Weight

656.12

Formula

C37H45Cl3N2O2
CAS No.
Unlabeled CAS

SMILES

O=C(N1C[C@@](CC[N+]2(CC3)CCC3(C4=CC=CC=C4)CC2)(C5=CC=C(Cl)C(Cl)=C5)CCC1)CC6=CC=CC(OC(C)C)=C6.[Cl-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Nolpitantium Related Classifications

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The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nolpitantium153050-21-6SR140333SR 140333SR-140333Neurokinin ReceptorNK receptorTachykinin receptorsubstance Ptachykininthalamic neuronInhibitorinhibitorinhibit

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