1. Anti-infection
  2. Influenza Virus
  3. Oseltamivir-d3

Oseltamivir-d3 is a deuterium labeled Oseltamivir. Oseltamivir is an influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC50s of 0.67, 0.9, 1.34 and 13 nM, respectively. Anti-influenza A and B agent[1].

For research use only. We do not sell to patients.

Oseltamivir-d<sub>3</sub> Chemical Structure

Oseltamivir-d3 Chemical Structure

CAS No. : 1093851-61-6

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Based on 1 publication(s) in Google Scholar

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Description

Oseltamivir-d3 is a deuterium labeled Oseltamivir. Oseltamivir is an influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC50s of 0.67, 0.9, 1.34 and 13 nM, respectively. Anti-influenza A and B agent[1].

Molecular Weight

315.42

Formula

C16H25D3N2O4

CAS No.
Unlabeled Cas

196618-13-0

Appearance

Solid

Color

White to off-white

SMILES

CCOC(C(C[C@@H]([C@H]1NC(C([2H])([2H])[2H])=O)N)=C[C@H]1OC(CC)CC)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (317.04 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1704 mL 15.8519 mL 31.7038 mL
5 mM 0.6341 mL 3.1704 mL 6.3408 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.1704 mL 15.8519 mL 31.7038 mL 79.2594 mL
5 mM 0.6341 mL 3.1704 mL 6.3408 mL 15.8519 mL
10 mM 0.3170 mL 1.5852 mL 3.1704 mL 7.9259 mL
15 mM 0.2114 mL 1.0568 mL 2.1136 mL 5.2840 mL
20 mM 0.1585 mL 0.7926 mL 1.5852 mL 3.9630 mL
25 mM 0.1268 mL 0.6341 mL 1.2682 mL 3.1704 mL
30 mM 0.1057 mL 0.5284 mL 1.0568 mL 2.6420 mL
40 mM 0.0793 mL 0.3963 mL 0.7926 mL 1.9815 mL
50 mM 0.0634 mL 0.3170 mL 0.6341 mL 1.5852 mL
60 mM 0.0528 mL 0.2642 mL 0.5284 mL 1.3210 mL
80 mM 0.0396 mL 0.1981 mL 0.3963 mL 0.9907 mL
100 mM 0.0317 mL 0.1585 mL 0.3170 mL 0.7926 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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