Penicillin G benzathine  (Synonyms: Benzathine benzylpenicillin)

Penicillin G benzathine (Benzathine benzylpenicillin) is an antibiotic against many bacterial infections^[1].

Penicillin G benzathine displays activity and antibacterial effect in CD-I mice infected with Staphylococcus aureus Smith^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

909.12

C₄₈H₅₆N₆O₈S₂

1538-09-6

Solid

Off-white to light yellow

O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC(CC3=CC=CC=C3)=O)N1C2=O)O.O=C([C@@H](C(C)(C)S[C@]4([H])[C@@H]5NC(CC6=CC=CC=C6)=O)N4C5=O)O.C7(CNCCNCC8=CC=CC=C8)=CC=CC=C7

Room temperature in continental US; may vary elsewhere.

• [1]. Bowen AC, et al. Short-course oral co-trimoxazole versus intramuscular benzathine benzylpenicillin for impetigo in a highly endemic region: an open-label, randomised, controlled, non-inferiority trial. Lancet. 2014 Dec 13;384(9960):2132-40.  [Content Brief]

  [2]. J A Yurchenco, et al. Substituted Penicillin Amides. Duration of Antibacterial Activity (Depot Effect) in Experimental Infections in Mice. Chemotherapy . 1972;17(6):405-15.  [Content Brief]