2. GPCR/G Protein Autophagy Apoptosis Neuronal Signaling Immunology/Inflammation
  3. Dopamine Receptor Adrenergic Receptor 5-HT Receptor Autophagy Histamine Receptor Apoptosis
  4. Perphenazine-d4

Perphenazine-d4 is the deuterium labeled Perphenazine. Perphenazine is a typical antipsychotic agent, inhibits 5-HT2Areceptor, Alpha-1A adrenergic receptor, Dopamine receptor D2/D3, D2L receptor, and Histamine H1 receptor, with Ki values of 5.6, 10, 0.765/0.13, 3.4, and 8 nM, respectively.

For research use only. We do not sell to patients.

Perphenazine-d<sub>4</sub> Chemical Structure

Perphenazine-d4 Chemical Structure

CAS No. : 155593-75-2

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1 mg USD 270 In-stock
5 mg USD 830 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Perphenazine-d4:

Perphenazine-d4 Related Antibodies

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  • Biological Activity

  • Purity & Documentation

  • References

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Description

Perphenazine-d4 is the deuterium labeled Perphenazine. Perphenazine is a typical antipsychotic agent, inhibits 5-HT2Areceptor, Alpha-1A adrenergic receptor, Dopamine receptor D2/D3, D2L receptor, and Histamine H1 receptor, with Ki values of 5.6, 10, 0.765/0.13, 3.4, and 8 nM, respectively.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Perphenazine-d4 Related Antibodies
Molecular Weight

407.99

Formula

C21H22D4ClN3OS
CAS No.
Unlabeled CAS

58-39-9
Appearance

Solid

Color

White to off-white

SMILES

OCCN(CC1)CCN1CCCN2C3=C([2H])C(Cl)=C([2H])C=C3SC4=CC([2H])=CC([2H])=C42
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (245.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4510 mL 12.2552 mL 24.5104 mL
5 mM 0.4902 mL 2.4510 mL 4.9021 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

COA (249 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4510 mL 12.2552 mL 24.5104 mL 61.2760 mL
5 mM 0.4902 mL 2.4510 mL 4.9021 mL 12.2552 mL
10 mM 0.2451 mL 1.2255 mL 2.4510 mL 6.1276 mL
15 mM 0.1634 mL 0.8170 mL 1.6340 mL 4.0851 mL
20 mM 0.1226 mL 0.6128 mL 1.2255 mL 3.0638 mL
25 mM 0.0980 mL 0.4902 mL 0.9804 mL 2.4510 mL
30 mM 0.0817 mL 0.4085 mL 0.8170 mL 2.0425 mL
40 mM 0.0613 mL 0.3064 mL 0.6128 mL 1.5319 mL
50 mM 0.0490 mL 0.2451 mL 0.4902 mL 1.2255 mL
60 mM 0.0409 mL 0.2043 mL 0.4085 mL 1.0213 mL
80 mM 0.0306 mL 0.1532 mL 0.3064 mL 0.7660 mL
100 mM 0.0245 mL 0.1226 mL 0.2451 mL 0.6128 mL
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Perphenazine-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Perphenazine-d4155593-75-2Dopamine ReceptorAdrenergic Receptor5-HT ReceptorAutophagyHistamine ReceptorApoptosisBeta ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorInhibitorinhibitorinhibit

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