2. GPCR/G Protein Metabolic Enzyme/Protease
  3. Prostaglandin Receptor Endogenous Metabolite
  4. Prostaglandin D2-d9

Prostaglandin D2-d9  (Synonyms: PGD2-d9)

Cat. No.: HY-101988S1 Purity: ≥99.0%
COA Handling Instructions

Molarity Calculator

Prostaglandin D2-d9 is the deuterium labeled Prostaglandin D2. Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals[1]. Prostaglandin D2 is one of the most potent endogenous sleep promoting substances[2]. PGD2 plays a protective role by suppressing inflammation[3].

For research use only. We do not sell to patients.

Prostaglandin D2-d<sub>9</sub> Chemical Structure

Prostaglandin D2-d9 Chemical Structure

CAS No. : 2254642-52-7

Size Price Stock Quantity
Solvent
100 μg (276.61 μM * 1 mL in Methyl acetate) USD 860 In-stock
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Prostaglandin D2-d9:

Prostaglandin D2-d9 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Prostaglandin D2-d9 is the deuterium labeled Prostaglandin D2. Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals[1]. Prostaglandin D2 is one of the most potent endogenous sleep promoting substances[2]. PGD2 plays a protective role by suppressing inflammation[3].

IC50 & Target

DP

 

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Prostaglandin D2-d9 Related Antibodies
Molecular Weight

361.52

Formula

C20H23D9O5
CAS No.
Unlabeled Cas

41598-07-6
Appearance

Liquid

Color

Colorless to light yellow

SMILES

O[C@@H]1[C@@H]([C@H](C(C1)=O)/C=C/[C@H](CC([2H])(C([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H])[2H])O)C/C=C\CCCC(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Solution, -20°C, 2 years
Solvent & Solubility
In Vitro: 

Ethanol : 75 mg/mL (207.46 mM; Need ultrasonic and warming)

DMSO : 50 mg/mL (138.30 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

COA (255 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / Ethanol 1 mM 2.7661 mL 13.8305 mL 27.6610 mL 69.1525 mL
5 mM 0.5532 mL 2.7661 mL 5.5322 mL 13.8305 mL
10 mM 0.2766 mL 1.3830 mL 2.7661 mL 6.9152 mL
15 mM 0.1844 mL 0.9220 mL 1.8441 mL 4.6102 mL
20 mM 0.1383 mL 0.6915 mL 1.3830 mL 3.4576 mL
25 mM 0.1106 mL 0.5532 mL 1.1064 mL 2.7661 mL
30 mM 0.0922 mL 0.4610 mL 0.9220 mL 2.3051 mL
40 mM 0.0692 mL 0.3458 mL 0.6915 mL 1.7288 mL
50 mM 0.0553 mL 0.2766 mL 0.5532 mL 1.3830 mL
60 mM 0.0461 mL 0.2305 mL 0.4610 mL 1.1525 mL
80 mM 0.0346 mL 0.1729 mL 0.3458 mL 0.8644 mL
100 mM 0.0277 mL 0.1383 mL 0.2766 mL 0.6915 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Prostaglandin D2-d9 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Prostaglandin D2-d92254642-52-7PGD2-d9Prostaglandin ReceptorEndogenous MetaboliteInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Prostaglandin D2-d9
Cat. No.:
HY-101988S1
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.