1. Immunology/Inflammation
  2. NTPDase
  3. PSB069

PSB069 bearing a p-chlorophenylamino residue is a potent, well-tolerated and nonselective NTPDases1, 2, 3 inhibitor(Ki=16~18 μM).

For research use only. We do not sell to patients.

PSB069 Chemical Structure

PSB069 Chemical Structure

CAS No. : 78510-31-3

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Description

PSB069 bearing a p-chlorophenylamino residue is a potent, well-tolerated and nonselective NTPDases1, 2, 3 inhibitor(Ki=16~18 μM)[1].

IC50 & Target

Ki: 16~18 μM (NTPDases1, 2, 3)[1]

In Vitro

PSB069 is a nonselective NTPDases1, 2, 3 inhibitor(Ki=16~18 μM)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

450.83

Formula

C20H12ClN2NaO5S

CAS No.
Unlabeled CAS

SMILES

O=S(C(C(N)=C1C2=O)=CC(NC3=CC=C(Cl)C=C3)=C1C(C4=C2C=CC=C4)=O)(O[Na])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 45 mg/mL (99.82 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2181 mL 11.0907 mL 22.1813 mL
5 mM 0.4436 mL 2.2181 mL 4.4363 mL
View the Complete Stock Solution Preparation Table
  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2181 mL 11.0907 mL 22.1813 mL 55.4533 mL
5 mM 0.4436 mL 2.2181 mL 4.4363 mL 11.0907 mL
10 mM 0.2218 mL 1.1091 mL 2.2181 mL 5.5453 mL
15 mM 0.1479 mL 0.7394 mL 1.4788 mL 3.6969 mL
20 mM 0.1109 mL 0.5545 mL 1.1091 mL 2.7727 mL
25 mM 0.0887 mL 0.4436 mL 0.8873 mL 2.2181 mL
30 mM 0.0739 mL 0.3697 mL 0.7394 mL 1.8484 mL
40 mM 0.0555 mL 0.2773 mL 0.5545 mL 1.3863 mL
50 mM 0.0444 mL 0.2218 mL 0.4436 mL 1.1091 mL
60 mM 0.0370 mL 0.1848 mL 0.3697 mL 0.9242 mL
80 mM 0.0277 mL 0.1386 mL 0.2773 mL 0.6932 mL
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PSB069 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
PSB069
Cat. No.:
HY-103262
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