1. Others Membrane Transporter/Ion Channel Neuronal Signaling
  2. Isotope-Labeled Compounds Sodium Channel Calcium Channel
  3. Ranolazine-d5

Ranolazine-d5  (Synonyms: CVT 303-d5; RS 43285-003-d5)

Cat. No.: HY-B0280S
Handling Instructions

Ranolazine-d5 is the deuterium labeled Ranolazine. Ranolazine (CVT 303) is an anti-angina drug that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP)[1][2]. Ranolazine is also a partial fatty acid oxidation (FAO) inhibitor[3]. Antianginal agent.

For research use only. We do not sell to patients.

Ranolazine-d<sub>5</sub> Chemical Structure

Ranolazine-d5 Chemical Structure

CAS No. : 1092804-87-9

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Description

Ranolazine-d5 is the deuterium labeled Ranolazine. Ranolazine (CVT 303) is an anti-angina drug that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP)[1][2]. Ranolazine is also a partial fatty acid oxidation (FAO) inhibitor[3]. Antianginal agent.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

432.57

Formula

C24H28D5N3O4

CAS No.
Unlabeled CAS

95635-55-5

SMILES

CC(C=CC=C1C)=C1NC(CN(CC2)CCN2C([2H])([2H])C(O)([2H])C([2H])([2H])OC3=C(C=CC=C3)OC)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Ranolazine-d5
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HY-B0280S
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