2. Epigenetics TGF-beta/Smad
  3. PKC
  4. SAMβA TFA

SAMβA TFA is conjugated to the cell permeable peptide TAT47-57. SAMβA TFA, a rationally designed selective antagonist of Mfn1-βIIPKC association. SAMβA TFA is a selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats.

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SAMβA TFA Chemical Structure

SAMβA TFA Chemical Structure

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10 mg USD 304 In-stock
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Based on 1 publication(s) in Google Scholar

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SAMβA TFA Related Antibodies

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Description

SAMβA TFA is conjugated to the cell permeable peptide TAT47-57. SAMβA TFA, a rationally designed selective antagonist of Mfn1-βIIPKC association. SAMβA TFA is a selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats[1].

Molecular Weight

1168.22 (free acid)

Formula

C50H73N17O16. .xC2HF3O2
Unlabeled CAS

Appearance

Solid

Color

White to off-white

Sequence

Arg-Asn-Ala-Glu-Asn-Phe-Asp-Arg-Phe
Sequence Shortening

RNAENFDRF
SMILES

OC(C(F)(F)F)=O.OC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(N)=N)N)=O)CC(N)=O)=O)C)=O)CCC(O)=O)=O)CC(N)=O)=O)=O)CC(O)=O)=O)CCCNC(N)=N)=O)CC2=CC=CC=C2)=O.[x]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (Need ultrasonic)

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 98.91%

COA (242 KB) LCMS (101 KB)

Handling Instructions (2659 KB)
References
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SAMβA TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SAMβAPKCProtein kinase Ccell permeable peptide TAT47-57inhibitory peptide SAMβAMfn1-βIIPKC associationheart failureInhibitorinhibitorinhibit

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