Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 

Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 is a potent ruthenium-based dye. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can bu used as an effective quencher of quantum dots (QDs) fluorescence and the capture probe of virus antigen EV71. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can be used sensitive electrogenerated chemiluminescence (ECL) labels for detection of matrix metalloproteinases (MMPs)^[1][2][3].

Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can be used as a label to measure the hydrodynamic radii of intravitreal anti-VEGF drugs^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

1014.66

C₃₆H₂₉F₁₂N₇O₄P₂Ru

136724-73-7

Solid

Brown to red

O=C(C1=CC=[N](C2=C1)[Ru+2]34([N]5=CC=CC=C5C6=CC=CC=[N]36)([N]7=CC=CC=C7C8=CC=CC=[N]48)[N](C2=C9)=CC=C9C)ON(C%10=O)C(CC%10)=O.[F-][P+5]([F-])([F-])([F-])([F-])[F-].[F-][P+5]([F-])([F-])([F-])([F-])[F-]

Room temperature in continental US; may vary elsewhere.

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

• [1]. Chen L, et al. Dual-color fluorescence and homogeneous immunoassay for the determination of human enterovirus 71. Anal Chem. 2011 Oct 1;83(19):7316-22.  [Content Brief]

  [2]. Hirvonen LM, et al. Hydrodynamic Radii of Ranibizumab, Aflibercept and Bevacizumab Measured by Time-Resolved Phosphorescence Anisotropy. Pharm Res. 2016 Aug;33(8):2025-32.  [Content Brief]

  [3]. HongfangGao, et al. Highly selective electrogenerated chemiluminescence biosensor for simultaneous detection of matrix metalloproteinase-2 and matrix metalloproteinase-7 in cell secretions. Sensors and Actuators B: Chemical, December 2017, 69-76.