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  4. (S,S,S)-AHPC-Boc

(S,S,S)-AHPC-Boc  (Synonyms: (S,S,S)-VH032-Boc)

Cat. No.: HY-123109A Purity: 97.21%
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(S,S,S)-AHPC-Boc is the isomer of (S,R,S)-AHPC-Boc (HY-123109), and can be used as an experimental control. (S,R,S)-AHPC-Boc (VH032-Boc) is a ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC-Boc is used in PROTAC technology.

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(S,S,S)-AHPC-Boc Chemical Structure

(S,S,S)-AHPC-Boc Chemical Structure

CAS No. : 1797406-74-6

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Based on 1 publication(s) in Google Scholar

Other Forms of (S,S,S)-AHPC-Boc:

(S,S,S)-AHPC-Boc Related Antibodies

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Description

(S,S,S)-AHPC-Boc is the isomer of (S,R,S)-AHPC-Boc (HY-123109), and can be used as an experimental control. (S,R,S)-AHPC-Boc (VH032-Boc) is a ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC-Boc is used in PROTAC technology[1].

Molecular Weight

530.68

Formula

C27H38N4O5S
CAS No.
Unlabeled CAS

Appearance

Solid

Color

Light yellow to green yellow

SMILES

O=C(N1C[C@H](C[C@H]1C(NCC2=CC=C(C=C2)C3=C(N=CS3)C)=O)O)[C@H](C(C)(C)C)NC(OC(C)(C)C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (94.22 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8844 mL 9.4219 mL 18.8437 mL
5 mM 0.3769 mL 1.8844 mL 3.7687 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8844 mL 9.4219 mL 18.8437 mL 47.1094 mL
5 mM 0.3769 mL 1.8844 mL 3.7687 mL 9.4219 mL
10 mM 0.1884 mL 0.9422 mL 1.8844 mL 4.7109 mL
15 mM 0.1256 mL 0.6281 mL 1.2562 mL 3.1406 mL
20 mM 0.0942 mL 0.4711 mL 0.9422 mL 2.3555 mL
25 mM 0.0754 mL 0.3769 mL 0.7537 mL 1.8844 mL
30 mM 0.0628 mL 0.3141 mL 0.6281 mL 1.5703 mL
40 mM 0.0471 mL 0.2355 mL 0.4711 mL 1.1777 mL
50 mM 0.0377 mL 0.1884 mL 0.3769 mL 0.9422 mL
60 mM 0.0314 mL 0.1570 mL 0.3141 mL 0.7852 mL
80 mM 0.0236 mL 0.1178 mL 0.2355 mL 0.5889 mL
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(S,S,S)-AHPC-Boc Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(S,S,S)-AHPC-Boc1797406-74-6(S,S,S)-VH032-BocOthersubiquitouslyE3ligasecomplexesbifunctionaldegradationligandInhibitorinhibitorinhibit

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