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ASPN

" in MedChemExpress (MCE) Product Catalog:

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Inhibitors & Agonists

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Recombinant Proteins

Cat. No. Compare Product Name Species Source
  • HY-P72093

    ASPN; ASPN protein; ASPN_HUMAN; Asporin LRR class 1; ; Asporin; Asporin proteoglycan; FLJ20129; LRR class 1; Periodontal ligament associated protein 1; Periodontal ligament-associated protein 1; PLAP 1; PLAP-1; PLAP1; SLRR 1C; SLRR1C; Small leucine rich protein 1C

    Human E. coli
    ASPN protein acts as a negative regulator in periodontal ligament (PDL) differentiation and mineralization, preventing ossification and maintaining homeostasis of the tooth support system. It inhibits BMP2-induced cell differentiation by blocking the binding of BMP2 to BMPR1B, thereby preventing BMP-dependent activation of SMAD proteins. ASPN Protein, Human (His-SUMO) is the recombinant human-derived ASPN protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of ASPN Protein, Human (His-SUMO) is 348 a.a., with molecular weight of ~60 kDa.

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