2. Search Result
Search Result
Results for "

VDAC

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

1

Fluorescent Dye

1

Peptides

1

Antibodies

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15763
    Erastin
    Maximum Cited Publications
    311 Publications Verification

    		 VDAC Ferroptosis Cancer
    Erastin is a ferroptosis inducer. Erastin exhibits the mechanism of ferroptosis induction related to ROS and iron-dependent signaling. Erastin inhibits voltage-dependent anion channels (VDAC2/VDAC3) and accelerates oxidation, leading to the accumulation of endogenous reactive oxygen species. Erastin also disrupts mitochondrial permeability transition pore (mPTP) with anti-tumor activity .
    Erastin
  • HY-RS15629
    VDAC1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    VDAC1 Human Pre-designed siRNA Set A contains three designed siRNAs for VDAC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    VDAC1 Human Pre-designed siRNA Set A
    VDAC1 Human Pre-designed siRNA Set A
  • HY-RS15630
    VDAC2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    VDAC2 Human Pre-designed siRNA Set A contains three designed siRNAs for VDAC2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    VDAC2 Human Pre-designed siRNA Set A
    VDAC2 Human Pre-designed siRNA Set A
  • HY-RS15631
    VDAC3 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    VDAC3 Human Pre-designed siRNA Set A contains three designed siRNAs for VDAC3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    VDAC3 Human Pre-designed siRNA Set A
    VDAC3 Human Pre-designed siRNA Set A
  • HY-P10108
    Hexokinase II VDAC binding domain peptide

    Hxk2VBD peptide

    		 Hexokinase Neurological Disease
    Hexokinase II VDAC binding domain peptide (Hxk2VBD peptide) is a cell-permeable hexokinase II VDAC binding domain. Hexokinase II VDAC binding domain peptide inhibits mitochondrial localization of hexokinase 2 (HXK2). Hexokinase II VDAC binding domain peptide inhibits neurotrophic factor-directed axon outgrowth .
    Hexokinase II <em>VDAC</em> binding domain peptide
  • HY-108937
    NSC 15364
    5+ Cited Publications

    		 VDAC Apoptosis Cardiovascular Disease Neurological Disease
    NSC 15364 is an inhibitor of VDAC1 oligomerization and apoptosis .
    NSC 15364
  • HY-129122
    VBIT-4
    5+ Cited Publications

    		 VDAC Cardiovascular Disease Neurological Disease
    VBIT-4 is an inhibitor of voltage-dependent anion channel 1 (VDAC1) oligomerization with a binding affinity (Kd) of 17 μM. VBIT-4, as an apoptosis inhibitor, can be used for therapeutic purposes in apoptosis-associated disorders, such as neurodegenerative and cardiovascular diseases .
    VBIT-4
  • HY-128777
    WEHI-9625
    1 Publications Verification

    		 VDAC Apoptosis Cancer
    WEHI-9625 is a tricyclic sulfone, first-in-class inhibitor of apoptosis with an EC50 of 69 nM. WEHI-9625 binds to VDAC2 and promotes its ability to inhibit apoptosis driven by mouse BAK. WEHI-9625 is completely inactive against both human BAK and the closely related apoptosis effector BAX .
    WEHI-9625
  • HY-121693
    DIDS

    MDL101114ZA free base

    		 VDAC RAD51 Cancer
    DIDS is a dual inhibitor of ABCA1 and VDAC1. DIDS also inhibits RAD51, inhibiting RAD51-mediated homologous pairing and strand exchange reactions. DIDS inhibits anion exchange and binding to red blood cell membranes, inhibits the activation of caspase-3 and -9, and can be used in cancer research .
    DIDS
  • HY-D0086
    DIDS sodium salt
    5+ Cited Publications

    MDL101114ZA

    		 VDAC RAD51 Cancer
    DIDS sodium salt (MDL101114ZA) is a dual inhibitor of ABCA1 and VDAC1. DIDS also inhibits RAD51, inhibiting RAD51-mediated homologous pairing and strand exchange reactions. DIDS inhibits anion exchange and binding to red blood cell membranes, inhibits the activation of caspase-3 and -9, and can be used in cancer research .
    DIDS sodium salt
  • HY-161027
    DHP-B

    		Apoptosis Cancer
    DHP-B possesses anti-cancer activity and induces apoptosis. DHP-B covalently binds to Cys96 of CPT1A, blocks FAO, and disrupts the mitochondrial CPT1A-VDAC1 interaction, leading to increased mitochondrial permeability and reduced oxygen consumption and energy metabolism in CRC cells. DHP-B can be isolated from the plant Peperomia dindygulensis .
    DHP-B

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: