2. Metabolic Enzyme/Protease
  3. Liposome
  4. ssPalmO-Phe

SSPalmO-Phe is an ionizable cationic self-degradable disulfide-cleavable (SS-cleavable) proton-activated lipid-like material. It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for drug delivery.

For research use only. We do not sell to patients.

ssPalmO-Phe Chemical Structure

ssPalmO-Phe Chemical Structure

CAS No. : 2377474-67-2

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Based on 1 publication(s) in Google Scholar

ssPalmO-Phe Related Antibodies

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Description

SSPalmO-Phe is an ionizable cationic self-degradable disulfide-cleavable (SS-cleavable) proton-activated lipid-like material. It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for drug delivery.

Molecular Weight

1173.78

Formula

C70H112N2O8S2
CAS No.
Unlabeled CAS

Appearance

Solid

Color

White to off-white

SMILES

CCCCCCCC/C=C\CCCCCCCC(OC(C=C1)=CC=C1CC(OCCC(CC2)CCN2CCSSCCN(CC3)CCC3CCOC(CC4=CC=C(C=C4)OC(CCCCCCC/C=C\CCCCCCCC)=O)=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (85.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8519 mL 4.2597 mL 8.5195 mL
5 mM 0.1704 mL 0.8519 mL 1.7039 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.8519 mL 4.2597 mL 8.5195 mL 21.2987 mL
5 mM 0.1704 mL 0.8519 mL 1.7039 mL 4.2597 mL
10 mM 0.0852 mL 0.4260 mL 0.8519 mL 2.1299 mL
15 mM 0.0568 mL 0.2840 mL 0.5680 mL 1.4199 mL
20 mM 0.0426 mL 0.2130 mL 0.4260 mL 1.0649 mL
25 mM 0.0341 mL 0.1704 mL 0.3408 mL 0.8519 mL
30 mM 0.0284 mL 0.1420 mL 0.2840 mL 0.7100 mL
40 mM 0.0213 mL 0.1065 mL 0.2130 mL 0.5325 mL
50 mM 0.0170 mL 0.0852 mL 0.1704 mL 0.4260 mL
60 mM 0.0142 mL 0.0710 mL 0.1420 mL 0.3550 mL
80 mM 0.0106 mL 0.0532 mL 0.1065 mL 0.2662 mL
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ssPalmO-Phe Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ssPalmO-Phe2377474-67-2LiposomeInhibitorinhibitorinhibit

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