2. Metabolic Enzyme/Protease
  3. FXR
  4. Tauro-obeticholic acid

Tauro-obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an orally bioavailable farnesoid-X receptor (FXR) agonist.

For research use only. We do not sell to patients.

Tauro-obeticholic acid Chemical Structure

Tauro-obeticholic acid Chemical Structure

CAS No. : 863239-61-6

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Based on 1 publication(s) in Google Scholar

Other Forms of Tauro-obeticholic acid:

Tauro-obeticholic acid Related Antibodies

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Description

Tauro-obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an orally bioavailable farnesoid-X receptor (FXR) agonist[1].

In Vitro

Obeticholic acid is conjugated with taurine in the liver to form Tauro-obeticholic acid, which is secreted into bile. Microorganisms in the ileum and colon can deconjugate Tauro-obeticholic acid, converting it into the parent drug, which may then be reabsorbed or excreted in faeces[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Tauro-obeticholic acid Related Antibodies
Molecular Weight

527.76

Formula

C28H49NO6S
CAS No.
Unlabeled CAS

Appearance

Solid

Color

White to yellow

SMILES

C[C@H](CCC(NCCS(=O)(O)=O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])[C@H](O)[C@H](CC)[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Purity & Documentation

Purity: ≥98.0%

COA (250 KB)

Handling Instructions (2659 KB)
References
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Tauro-obeticholic acid Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tauro-obeticholic acid863239-61-6FXRNR1H4metabolite，livermicroorganismsileumcolonInhibitorinhibitorinhibit

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