2. Apoptosis
  3. Apoptosis
  4. Thrombospondin-1 (1016-1023) (human, bovine, mouse)

Thrombospondin-1 (1016-1023) (human, bovine, mouse) 

Cat. No.: HY-P0144 Purity: 99.08%
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Thrombospondin-1 (1016-1023) (human, bovine, mouse), is the C-terminal end of the native sequence of Thrombospondin-1 (TSP-1), is a CD47 agonist peptide.

For research use only. We do not sell to patients.

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Thrombospondin-1 (1016-1023) (human, bovine, mouse) Chemical Structure

Thrombospondin-1 (1016-1023) (human, bovine, mouse) Chemical Structure

CAS No. : 149234-04-8

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1 mg USD 55 In-stock
5 mg USD 140 In-stock
10 mg USD 225 In-stock
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Based on 1 publication(s) in Google Scholar

Thrombospondin-1 (1016-1023) (human, bovine, mouse) Related Antibodies

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Description

Thrombospondin-1 (1016-1023) (human, bovine, mouse), is the C-terminal end of the native sequence of Thrombospondin-1 (TSP-1), is a CD47 agonist peptide[1].

In Vitro

Thrombospondin-1 (1016-1023) (human, bovine, mouse) (4N1K; 100 µg/mL; for 60 min) treatment has induced both phosphatidylserine exposure and loss of cell membrane integrity in monocyte-derived immature dendritic cells (DCs). With peptide concentrations of 25-200 µg/mL, the number of annexin V+ cells increased with peptide concentration. Thrombospondin-1 (1016-1023) (human, bovine, mouse) reduces mitochondrial membrane potential and fragmented DNA in DCs[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Thrombospondin-1 (1016-1023) (human, bovine, mouse) Related Antibodies
Molecular Weight

1128.39

Formula

C56H81N13O10S
CAS No.
Unlabeled CAS

Appearance

Solid

Color

White to off-white

Sequence Shortening

RFYVVMWK
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 14.29 mg/mL (12.66 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8862 mL 4.4311 mL 8.8622 mL
5 mM 0.1772 mL 0.8862 mL 1.7724 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.8862 mL 4.4311 mL 8.8622 mL 22.1555 mL
5 mM 0.1772 mL 0.8862 mL 1.7724 mL 4.4311 mL
10 mM 0.0886 mL 0.4431 mL 0.8862 mL 2.2155 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Thrombospondin-1 (1016-1023) (human, bovine, mouse) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Thrombospondin-1 (1016-1023) (human, bovine, mouse)149234-04-8ApoptosisCD47 agonistTSP-1apoptosisInhibitorinhibitorinhibit

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