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  4. TREM-1 inhibitory peptide M3

TREM-1 inhibitory peptide M3 is a ligand-dependent TREM-1 antagonist. TREM-1 inhibitory peptide M3 can inhibit systemic and pulmonary pro-inflammatory cytokine and chemokine production and attenuate acute lung injury.

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TREM-1 inhibitory peptide M3 Chemical Structure

TREM-1 inhibitory peptide M3 Chemical Structure

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1 mg USD 60 In-stock
5 mg USD 125 In-stock
10 mg USD 188 In-stock
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Based on 1 publication(s) in Google Scholar

TREM-1 inhibitory peptide M3 Related Antibodies

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Description

TREM-1 inhibitory peptide M3 is a ligand-dependent TREM-1 antagonist. TREM-1 inhibitory peptide M3 can inhibit systemic and pulmonary pro-inflammatory cytokine and chemokine production and attenuate acute lung injury[1].

Molecular Weight

795.89

Formula

C36H53N13O8
Unlabeled CAS

Appearance

Solid

Color

White to off-white

Sequence

Arg-Gly-Phe-Phe-Arg-Gly-Gly
Sequence Shortening

RGFFRGG
SMILES

O=C(NCC(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CCCNC(N)=N)C(NCC(NCC(O)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (125.65 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.2565 mL 6.2823 mL 12.5645 mL
5 mM 0.2513 mL 1.2565 mL 2.5129 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.2565 mL 6.2823 mL 12.5646 mL 31.4114 mL
5 mM 0.2513 mL 1.2565 mL 2.5129 mL 6.2823 mL
10 mM 0.1256 mL 0.6282 mL 1.2565 mL 3.1411 mL
15 mM 0.0838 mL 0.4188 mL 0.8376 mL 2.0941 mL
20 mM 0.0628 mL 0.3141 mL 0.6282 mL 1.5706 mL
25 mM 0.0503 mL 0.2513 mL 0.5026 mL 1.2565 mL
30 mM 0.0419 mL 0.2094 mL 0.4188 mL 1.0470 mL
40 mM 0.0314 mL 0.1571 mL 0.3141 mL 0.7853 mL
50 mM 0.0251 mL 0.1256 mL 0.2513 mL 0.6282 mL
60 mM 0.0209 mL 0.1047 mL 0.2094 mL 0.5235 mL
80 mM 0.0157 mL 0.0785 mL 0.1571 mL 0.3926 mL
100 mM 0.0126 mL 0.0628 mL 0.1256 mL 0.3141 mL
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TREM-1 inhibitory peptide M3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TREM-1 inhibitory peptide M3OthersTREM-1pro-inflammatory cytokinechemokineacute lung injuryeCIRPInhibitorinhibitorinhibit

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