2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. Tropanserin

Tropanserin  (Synonyms: MDL 72422)

Cat. No.: HY-101050 Purity: 99.92%
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Tropanserin is a serotoninergic active compound, as well as a 5HT3 receptor antagonist. Tropanserin modulates Cardio-respiratory reflex effects of an exogenous serotonin challenge.

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Tropanserin Chemical Structure

Tropanserin Chemical Structure

CAS No. : 85181-40-4

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5 mg USD 110 In-stock
10 mg USD 175 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Tropanserin is a serotoninergic active compound, as well as a 5HT3 receptor antagonist. Tropanserin modulates Cardio-respiratory reflex effects of an exogenous serotonin challenge[1].

Molecular Weight

273.37

Formula

C17H23NO2
CAS No.
Unlabeled CAS

Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(O[C@@H]1C[C@@H](N2C)CC[C@@H]2C1)C3=CC(C)=CC(C)=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (182.90 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6580 mL 18.2902 mL 36.5805 mL
5 mM 0.7316 mL 3.6580 mL 7.3161 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.6580 mL 18.2902 mL 36.5805 mL 91.4511 mL
5 mM 0.7316 mL 3.6580 mL 7.3161 mL 18.2902 mL
10 mM 0.3658 mL 1.8290 mL 3.6580 mL 9.1451 mL
15 mM 0.2439 mL 1.2193 mL 2.4387 mL 6.0967 mL
20 mM 0.1829 mL 0.9145 mL 1.8290 mL 4.5726 mL
25 mM 0.1463 mL 0.7316 mL 1.4632 mL 3.6580 mL
30 mM 0.1219 mL 0.6097 mL 1.2193 mL 3.0484 mL
40 mM 0.0915 mL 0.4573 mL 0.9145 mL 2.2863 mL
50 mM 0.0732 mL 0.3658 mL 0.7316 mL 1.8290 mL
60 mM 0.0610 mL 0.3048 mL 0.6097 mL 1.5242 mL
80 mM 0.0457 mL 0.2286 mL 0.4573 mL 1.1431 mL
100 mM 0.0366 mL 0.1829 mL 0.3658 mL 0.9145 mL
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Tropanserin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tropanserin85181-40-4MDL 72422MDL72422MDL-724225-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorInhibitorinhibitorinhibit

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