2. Stem Cell/Wnt
  3. Wnt
  4. WIC1

WIC1 is a potent Wnt inhibitor. WIC1 can be used for the research of cancer.

For research use only. We do not sell to patients.

WIC1 Chemical Structure

WIC1 Chemical Structure

CAS No. : 943083-58-7

Size Price Stock Quantity
5 mg USD 55 In-stock
10 mg USD 90 In-stock
25 mg USD 190 In-stock
50 mg USD 305 In-stock
100 mg USD 490 In-stock
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Based on 1 publication(s) in Google Scholar

WIC1 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

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Description

WIC1 is a potent Wnt inhibitor. WIC1 can be used for the research of cancer[1].

In Vitro

WICl (10 nM, 100 nM, 10μM, 100 μM) decrease TFC/LEF luciferase reporter activity in BEAS2B cell[1].
WICl (10 nM, 100 nM, 10μM, 100 μM) shows minimal toxicity. WICl (1μM) displays a significant reduction in ABSC proliferation[1].
WICl decreases mRNA expression of 145 known downstream Wnt signaling target genes such as CCND1, MYC, and CTNNB1[1].
WICl (1μM) decreases the nuclear localization[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

WIC1 Related Antibodies
Molecular Weight

377.44

Formula

C22H23N3O3
CAS No.
Unlabeled Cas

Appearance

Solid

Color

Yellow to orange

SMILES

O=C(C1=CC2=CC=CC=C2OC1=O)NC3=CC=C(N4CCN(CC)CC4)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 1.67 mg/mL (4.42 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6494 mL 13.2471 mL 26.4943 mL
5 mM --- --- ---
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6494 mL 13.2471 mL 26.4943 mL 66.2357 mL
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WIC1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

WIC1943083-58-7WIC 1WIC-1WntcancerTFC/LEF luciferase reporterInhibitorinhibitorinhibit

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