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  3. Fluorescent Dye
  4. ZY-2

ZY-2 is a specific fluorescent probe for pyruvate kinase M2 (PKM2). ZY-2 can image in PKM2-positive cells in a time- and concentration-dependent manner. ZY-2 can be used for the detection of cancer cells.

For research use only. We do not sell to patients.

ZY-2 Chemical Structure

ZY-2 Chemical Structure

Size Price Stock Quantity
1 mg USD 350 In-stock
5 mg USD 786 In-stock
10 mg USD 1180 In-stock
25 mg USD 2244 In-stock
50 mg USD 3366 In-stock
100 mg USD 5050 In-stock
200 mg   Get quote  
500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

ZY-2 Related Antibodies

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Description

ZY-2 is a specific fluorescent probe for pyruvate kinase M2 (PKM2). ZY-2 can image in PKM2-positive cells in a time- and concentration-dependent manner. ZY-2 can be used for the detection of cancer cells[1].

Molecular Weight

765.94

Formula

C40H43N7O5S2
Unlabeled CAS

Appearance

Solid

Color

Orange to red

SMILES

CN1C2=C(SC(S(C)=O)=C2)C3=C1C(N(N=C3)CC4=CC(NC(CN5CCN(C6=CC=C(C=C6)/C=C/C7=CC=[N+](CC)C=C7)CC5)=O)=CC=C4)=O.CC([O-])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (130.56 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3056 mL 6.5279 mL 13.0559 mL
5 mM 0.2611 mL 1.3056 mL 2.6112 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3056 mL 6.5279 mL 13.0559 mL 32.6396 mL
5 mM 0.2611 mL 1.3056 mL 2.6112 mL 6.5279 mL
10 mM 0.1306 mL 0.6528 mL 1.3056 mL 3.2640 mL
15 mM 0.0870 mL 0.4352 mL 0.8704 mL 2.1760 mL
20 mM 0.0653 mL 0.3264 mL 0.6528 mL 1.6320 mL
25 mM 0.0522 mL 0.2611 mL 0.5222 mL 1.3056 mL
30 mM 0.0435 mL 0.2176 mL 0.4352 mL 1.0880 mL
40 mM 0.0326 mL 0.1632 mL 0.3264 mL 0.8160 mL
50 mM 0.0261 mL 0.1306 mL 0.2611 mL 0.6528 mL
60 mM 0.0218 mL 0.1088 mL 0.2176 mL 0.5440 mL
80 mM 0.0163 mL 0.0816 mL 0.1632 mL 0.4080 mL
100 mM 0.0131 mL 0.0653 mL 0.1306 mL 0.3264 mL
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ZY-2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ZY-2ZY2ZY 2Fluorescent DyecancerInhibitorinhibitorinhibit

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