1. Membrane Transporter/Ion Channel
  2. Sodium Channel
  3. β-Pompilidotoxin TFA

β-Pompilidotoxin TFA  (Synonyms: β-PMTX TFA)

Cat. No.: HY-P1084A
Handling Instructions

β-Pompilidotoxin TFA (β-PMTX TFA), a wasp venom, can slow sodium channel inactivation and increases steady-state sodium current in cells.

For research use only. We do not sell to patients.

β-Pompilidotoxin TFA Chemical Structure

β-Pompilidotoxin TFA Chemical Structure

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Description

β-Pompilidotoxin TFA (β-PMTX TFA), a wasp venom, can slow sodium channel inactivation and increases steady-state sodium current in cells[1].

In Vitro

β-Pompilidotoxin TFA (β-PMTX TFA) increases resurgent current in wild-type neurons and induced resurgent current in med neurons. β-Pompilidotoxin TFA (10 μM) modestly but significantly increased the decay time constant (τdecay) of currents evoked by a step from -90 to 0 mV from 0.52 to 0.73 msec in wild-type Purkinje cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1671.90

Formula

C73H125F3N22O19

Unlabeled CAS

Sequence

Arg-Ile-Lys-Ile-Gly-Leu-Phe-Asp-Gln-Leu-Ser-Arg-Leu-NH2

Sequence Shortening

RIKIGLFDQLSRL-NH2

SMILES

[RIKIGLFDQLSRL-NH2 (TFA salt)]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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β-Pompilidotoxin TFA
Cat. No.:
HY-P1084A
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