1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. Calcium Channel
  3. ω-Conotoxin GVIA TFA

ω-Conotoxin GVIA TFA is an inhibitor of the N-type Ca2+ channel.

For research use only. We do not sell to patients.

ω-Conotoxin GVIA TFA Chemical Structure

ω-Conotoxin GVIA TFA Chemical Structure

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100 μg USD 135 In-stock
500 μg USD 340 In-stock
1 mg USD 550 In-stock
5 mg USD 1380 In-stock
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Customer Review

Based on 2 publication(s) in Google Scholar

Other Forms of ω-Conotoxin GVIA TFA:

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  • Biological Activity

  • Purity & Documentation

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Description

ω-Conotoxin GVIA TFA is an inhibitor of the N-type Ca2+ channel[1].

In Vitro

ω-conotoxin GVIA (50 nM, 50 nL) inhibits the effects of urotensin II (UII)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

3151.37 (free base)

Formula

C120H182N38O43S6.xC2HF3O2

Unlabeled CAS

Appearance

Solid

Color

White to off-white

Sequence

Cys-Lys-Ser-{Hyp}-Gly-Ser-Ser-Cys-Ser-{Hyp}-Thr-Ser-Tyr-Asn-Cys-Cys-Arg-Ser-Cys-Asn-{Hyp}-Tyr-Thr-Lys-Arg-Cys-Tyr-NH2 (Disulfide bridge: Cys1-Cys16; Cys8-Cys19; Cys15-Cys26)

Sequence Shortening

CKS-{Hyp}-GSSCS-{Hyp}-TSYNCCRSCN-{Hyp}-YTKRCY-NH2 (Disulfide bridge: Cys1-Cys16; Cys8-Cys19; Cys15-Cys26)

SMILES

[CKS-{Hyp}-GSSCS-{Hyp}-TSYNCCRSCN-{Hyp}-YTKRCY-NH2 (Disulfide bridge: Cys1-Cys16; Cys8-Cys19; Cys15-Cys26) (TFA salt)]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (Need ultrasonic)

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Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.33%

References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
ω-Conotoxin GVIA TFA
Cat. No.:
HY-P0189A
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