ω-Tbo-IT1 

ω-Tbo-IT1 is a peptide toxin that can be isolated from the venom of Tibellus oblongus.ω-Tbo-IT1 is an inhibitor of insect calcium channel^[1].

4332.05

C₁₇₁H₂₈₅N₆₁O₅₃S₉

Cys-Ala-Ser-Lys-Asn-Glu-Arg-Cys-Gly-Asn-Ala-Leu-Tyr-Gly-Thr-Lys-Gly-Pro-Gly-Cys-Cys-Asn-Gly-Lys-Cys-Ile-Cys-Arg-Thr-Val-Pro-Arg-Lys-Gly-Val-Asn-Ser-Cys-Arg-Cys-Met (Disulfide bridge: Cys1-Cys21; Cys8-Cys25; Cys20-Cys40; Cys27-Cys38)

CASKNERCGNALYGTKGPGCCNGKCICRTVPRKGVNSCRCM (Disulfide bridge: Cys1-Cys21; Cys8-Cys25; Cys20-Cys40; Cys27-Cys38)

O=C(N[C@@H](C)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H](CC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CSSC[C@@H](C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CSSC[C@@H](C(N[C@H]1CCCNC(N)=N)=O)NC2=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@H](O)C)C(N[C@@H](C(C)C)C(N3[C@@H](CCC3)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(NCC(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(N[C@H]2CO)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC4=O)C(NCC(N[C@@H](CC(N)=O)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CC5=CC=C(C=C5)O)C(NCC(N[C@@H]([C@H](O)C)C(N[C@@H](CCCCN)C(NCC(N6[C@@H](CCC6)C(NCC(N[C@H]7CSSC[C@@H](C(N[C@@H](CCSC)C(O)=O)=O)NC1=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CSSC[C@@H](C(N[C@@H](CC(N)=O)C(NCC(N[C@H]4CCCCN)=O)=O)=O)NC7=O)N

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Mikov AN, et al. ω-Tbo-IT1-New Inhibitor of Insect Calcium Channels Isolated from Spider Venom. Sci Rep. 2015 Nov 27;5:17232.  [Content Brief]