2. Natural Products
  3. Disease Research Fields Plants Ketones, Aldehydes, Acids
  4. Liliaceae Metabolic Disease
  5.  Allium sativum Linn.
  6. γ-Glutamyl-S-allylcysteine

γ-Glutamyl-S-allylcysteine  (Synonyms: L-γ-Glutamyl-(S)-Allyl-Cysteine)

Cat. No.: HY-N9413 Purity: 99.94%
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γ-Glutamyl-S-allylcysteine (L-γ-Glutamyl-(S)-Allyl-Cysteine) is a naturally occurring organosulfur compound found in garlic. γ-Glutamyl-S-allylcysteine has antiglycative effect and shows radical-scavenging and metal-chelating capacities.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

γ-Glutamyl-S-allylcysteine Chemical Structure

γ-Glutamyl-S-allylcysteine Chemical Structure

CAS No. : 91216-95-4

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in Water
ready for reconstitution
 USD 330 In-stock
Solution
10 mM * 1 mL in Water USD 330 In-stock
Solid
5 mg USD 300 In-stock
10 mg USD 480 In-stock
25 mg USD 950 In-stock
50 mg USD 1450 In-stock
100 mg   Get quote  
200 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

γ-Glutamyl-S-allylcysteine Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

γ-Glutamyl-S-allylcysteine (L-γ-Glutamyl-(S)-Allyl-Cysteine) is a naturally occurring organosulfur compound found in garlic. γ-Glutamyl-S-allylcysteine has antiglycative effect and shows radical-scavenging and metal-chelating capacities[1][2].

In Vitro

γ-Glutamyl-S-allylcysteine (L-γ-Glutamyl-(S)-Allyl-Cysteine; 0.1-2.5 mg/mL) inhibits the increase of fluorescence intensity at about 440 nm in a concentration-dependent manner and reduces reacted free lysine side chains[1].
γ-Glutamyl-S-allylcysteine (2.5 mg/mL) prevents Glycation-specific decline in BSA α-helix content and increase in β-sheet in vitro[1].
γ-Glutamyl-S-allylcysteine (2.5 mg/mL) suppresses protein crosslinking to form polymers[1].
γ-Glutamyl-S-allylcysteine (10, 40, 160 μg/mL) shows radical-scavenging and metal-chelating capacities[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

γ-Glutamyl-S-allylcysteine Related Antibodies
Molecular Weight

290.34

Formula

C11H18N2O5S
CAS No.
Appearance

Solid

Color

White to off-white

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 33.33 mg/mL (114.80 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4442 mL 17.2212 mL 34.4424 mL
5 mM 0.6888 mL 3.4442 mL 6.8885 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 25 mg/mL (86.11 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.4442 mL 17.2212 mL 34.4424 mL 86.1059 mL
5 mM 0.6888 mL 3.4442 mL 6.8885 mL 17.2212 mL
10 mM 0.3444 mL 1.7221 mL 3.4442 mL 8.6106 mL
15 mM 0.2296 mL 1.1481 mL 2.2962 mL 5.7404 mL
20 mM 0.1722 mL 0.8611 mL 1.7221 mL 4.3053 mL
25 mM 0.1378 mL 0.6888 mL 1.3777 mL 3.4442 mL
30 mM 0.1148 mL 0.5740 mL 1.1481 mL 2.8702 mL
40 mM 0.0861 mL 0.4305 mL 0.8611 mL 2.1526 mL
50 mM 0.0689 mL 0.3444 mL 0.6888 mL 1.7221 mL
60 mM 0.0574 mL 0.2870 mL 0.5740 mL 1.4351 mL
80 mM 0.0431 mL 0.2153 mL 0.4305 mL 1.0763 mL
100 mM 0.0344 mL 0.1722 mL 0.3444 mL 0.8611 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

γ-Glutamyl-S-allylcysteine91216-95-4L-γ-Glutamyl-(S)-Allyl-CysteineOthersInhibitorinhibitorinhibit

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