1. Cell Cycle/DNA Damage
    Stem Cell/Wnt
    Cytoskeleton
    TGF-beta/Smad
  2. ROCK
  3. ROCK-IN-1

ROCK-IN-1 

Cat. No.: HY-U00351
Handling Instructions

ROCK-IN-1 is a potent inhibitor of ROCK, with an IC50 of 1.2 nM for ROCK2.

For research use only. We do not sell to patients.

ROCK-IN-1 Chemical Structure

ROCK-IN-1 Chemical Structure

CAS No. : 934387-35-6

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Description

ROCK-IN-1 is a potent inhibitor of ROCK, with an IC50 of 1.2 nM for ROCK2.

IC50 & Target[1]

ROCK2

1.2 nM (IC50)

In Vitro

ROCK-IN-1 shows potent cellular efficacy, with an EC50 of 200 nM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

335.37

Formula

C₂₀H₁₈FN₃O

CAS No.

934387-35-6

SMILES

O=C(C1=CC(C2=CC=C(F)C=C2)=C(C(N)C)C=C1)NC3=CC=NC=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

ROCK-IN-1ROCKRho-associated protein kinaseRho-associated kinaseRho-kinaseROKInhibitorinhibitorinhibit

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