1. Neuronal Signaling
    Stem Cell/Wnt
  2. γ-secretase
  3. γ-Secretase modulator 11

γ-Secretase modulator 11 

Cat. No.: HY-147720
Handling Instructions

5-{8-[(3,4'- difluoro [1,1'- biphenyl]-4-yl) methoxy] - 2-methylimidazo [1,2-a] pyridin-3-yl}-n-methylpyridin-2-formamide (1o) showed high potency in vitro and brain exposure, inducing brain a β 42 levels were significantly reduced and showed undetectable inhibition of cytochrome P450 enzymes. In addition, compound 1o showed excellent anti cognitive deficit effect in AD model mice.

For research use only. We do not sell to patients.

γ-Secretase modulator 11 Chemical Structure

γ-Secretase modulator 11 Chemical Structure

CAS No. : 2434630-29-0

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Description

5-{8-[(3,4'- difluoro [1,1'- biphenyl]-4-yl) methoxy] - 2-methylimidazo [1,2-a] pyridin-3-yl}-n-methylpyridin-2-formamide (1o) showed high potency in vitro and brain exposure, inducing brain a β 42 levels were significantly reduced and showed undetectable inhibition of cytochrome P450 enzymes. In addition, compound 1o showed excellent anti cognitive deficit effect in AD model mice.

Molecular Weight

484.50

Formula

C28H22F2N4O2

CAS No.
SMILES

O=C(C1=NC=C(C2=C(C)N=C3C(OCC4=CC=C(C5=CC=C(F)C=C5)C=C4F)=CC=CN32)C=C1)NC

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Please store the product under the recommended conditions in the Certificate of Analysis.

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γ-Secretase modulator 11
Cat. No.:
HY-147720
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