Search Result
Results for "
2-2-nitrobenzylidene-3-oxobutanoic-acid-2-acetoxy-2-methylpropyl-ester-d6
" in MedChemExpress (MCE) Product Catalog:
3
Biochemical Assay Reagents
5
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-W007926
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- HY-W006057
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- HY-W297715
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- HY-W007926R
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Endogenous Metabolite
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Others
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2-Oxobutanoic acid (Standard) is the analytical standard of 2-Oxobutanoic acid. This product is intended for research and analytical applications. 2-Oxobutanoic acid is a product in the enzymatic cleavage of cystathionine.
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- HY-150628S
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- HY-W009973S
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- HY-137877
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4-Methylumbelliferyl acetate
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Glutathione S-transferase
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Others
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7-Acetoxy-4-methylcoumarin is an inhibitor of GST.7-Acetoxy-4-methylcoumarin inhibits AFB1-DNA binding in vitro with 36.7% inhibition .
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- HY-131127
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AMQI
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Cholinesterase (ChE)
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Others
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7-Acetoxy-1-methylquinolinium iodide (AMQI) is a fluorogenic substrate for cholinesterase (Ex = 320 nm, Em = 410 nm). Hydrolysis of 7-acetoxy-1-methylquinolinium iodide is used at the fluorometric flow system for the detection and identification of inhibitors. .
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- HY-N1715
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2-Acetoxy-3-deacetoxycaesaldekarin e (compound 11) is a furanoditerpene that can be found in Caesalpinia crista .
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- HY-N1595
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16-Acetoxy-7-O-acetylhorminone is a compound isolated from the leaves of Rabdosia lophanthoides var. gerardiana .
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- HY-W011324
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- HY-W014504
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- HY-W014504S1
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Isotope-Labeled Compounds
Endogenous Metabolite
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2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid-d7 is the deuterium labeled 2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid. 2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid is an endogenous metabolite.
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- HY-N2677
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Others
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Others
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5-Hydroxy-7-acetoxy-8-methoxyflavone (compound F24) is a flavone .
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- HY-W016798
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- HY-A0025
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Biochemical Assay Reagents
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Others
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(R)-2-acetoxy-2-phenylacetic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W007573
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- HY-W107466
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Antibiotic
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Infection
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4-((4-((4-Aminophenyl)sulfonyl)phenyl)amino)-4-oxobutanoic acid is a sulfonamide antiinfective agent .
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- HY-N9121
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Others
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Others
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8β-(4-Acetoxy-5-hydroxytigloyloxy)costunolide (compound 5) is a sesquiterpene lactone that can be isolated from Stevia alpina var. glutinosa .
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- HY-P0041A
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- HY-W017069
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Amino Acid Derivatives
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Others
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(S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(allyloxy)-4-oxobutanoic acid is an aspartic acid derivative .
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- HY-W002301
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Amino Acid Derivatives
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Others
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(2S)-4-(benzyloxy)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-4-oxobutanoic acid is an aspartic acid derivative .
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- HY-136071
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- HY-136070
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- HY-N1803
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11,12-Dehydroursolic lactone acetate
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3-Acetoxy-11-ursen-28,13-olide (11,12-dehydroursolic lactone acetate) is a reduction product of 11-ketoursolic acid .
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- HY-W006057AS17
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Endogenous Metabolite
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Others
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3-Methyl-2-oxobutanoic acid- 13C2 is the 13C labeled Sodium 3-methyl-2-oxobutanoate[1]. Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli[2][3][4].
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- HY-N10439
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Glucosidase
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Inflammation/Immunology
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3β-Acetoxy-hop-22(29)-ene (compound 1) is a potent anti-inflammatory agent. 3β-Acetoxy-hop-22(29)-ene shows high inhibitory activity of yeast α-glucosidase, with an IC50 of 5.74 μM. 3β-Acetoxy-hop-22(29)-ene inhibits MPO (myeloperoxidase) activity in a dose-dependent manner in mouse ear edema model induced by 12-O-tetradecanoylphorbol acetate (TPA), with an IC50 of 0.23 μmol/ear .
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- HY-14656S1
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- HY-Z0615
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Boc-L-Asp(OBn)-OH
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(2S)-4-(Benzyloxy)-2-[(tert-butoxycarbonyl)amino]-4-oxobutanoic acid is an aspartic acid derivative .
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- HY-N8134
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Dipeptidyl Peptidase
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Metabolic Disease
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2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one is a natural product found in the leaves and stem bark of M. glabra. 2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one displays binding affinities with dipeptidyl peptidase-4 (DPP-4) and α-Amylase. 2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one has potential antidiabetic activities .
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- HY-P10200
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Bacterial
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Infection
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CP7-FP13-2 is a peptide with antivirulence factor and antibacterial activity. CP7-FP13-2 inhibits the formation of Staphylococcus aureus biofilm and has good antibacterial efficacy in mice .
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- HY-P3462
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CGRP Receptor
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Metabolic Disease
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Cagrilintide is an investigational novel long-acting acylated amylin analogue, acts as nonselective amylin receptors (AMYR) and calcitonin G protein-coupled receptor (CTR) agonist. Cagrilintide induces significant weight loss and reduces food intake. Cagrilintide has the potential for the research of obesity .
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- HY-P3462A
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CGRP Receptor
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Metabolic Disease
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Cagrilintide acetate is a non-selective AMYR/CTR agonist and long-acting acylated amylase analogue. Cagrilintide acetate causes a reduction in food intake and significant weight loss in a dose-dependent manner. Cagrilintide acetate can be used in obesity studies .
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- HY-P5161A
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GCGR
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Metabolic Disease
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FC382K10W15 TFA is a glucagon analogue and GLP-1R/GCGR agonist. FC382K10W15 TFA can be used in type 2 diabetes research .
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- HY-P3143
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PD-1/PD-L1
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Cancer
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BMSpep-57 is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC50 of 7.68 nM. BMSpep-57 binds to PD-L1 with Kds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 facilitates T cell function by in creasing IL-2 production in PBMCs .
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- HY-P3143A
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PD-1/PD-L1
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Cancer
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BMSpep-57 hydrochloride is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC50 of 7.68 nM. BMSpep-57 hydrochloride binds to PD-L1 with Kds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 hydrochloride facilitates T cell function by in creasing IL-2 production in PBMCs .
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- HY-P1162
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- HY-126220
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Fluorescent Dye
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Others
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KMG-301AM is the acetoxy methyl esterified form of KMG-301. KMG-301AM successfully accumulates in mitochondria and then it is hydrolyzed to KMG-301. KMG-301 is an Mg 2+-selective fluorescent probe functional in mitochondria in intact cells. Since the mitochondrial membrane is impermeable to KMG-301, it is not released upon depolarization of the mitochondrial membrane potential. KMG-301 can indicate changes in mitochondrial Mg2+ concentration and shows Mg 2+ transport across the mitochondrial membrane in the early phases of a cellular model .
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- HY-126220A
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Fluorescent Dye
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Others
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KMG-301AM TFA is the acetoxy methyl esterified form of KMG-301. KMG-301AM TFA successfully accumulates in mitochondria and then it is hydrolyzed to KMG-301. KMG-301 is an Mg 2+-selective fluorescent probe functional in mitochondria in intact cells. Since the mitochondrial membrane is impermeable to KMG-301, it is not released upon depolarization of the mitochondrial membrane potential. KMG-301 can indicate changes in mitochondrial Mg2+ concentration and shows Mg 2+ transport across the mitochondrial membrane in the early phases of a cellular model .
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- HY-W000978
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Isobutylboronic acid
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Biochemical Assay Reagents
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Others
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(2-Methylpropyl)boronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-P4895
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Oxytocin Receptor
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Neurological Disease
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(d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin (OVT) is an oxytocin receptor antagonist. (d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin can be used for the research of neurological disease .
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- HY-42034
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Dihydroquinine
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Hydroquinine is a cinchona alkaloid, can be used in the preparation of its derivatives such as C9 epihydroquinine, 9-acetoxy-10,11-dihydroquinine and 10,11-dihydroquinine monohydrochloride .
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- HY-B1908
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SF-837; Antibiotic SF-837
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Bacterial
Antibiotic
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Infection
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Midecamycin, an acetoxy-substituted macrolide antibiotic, is tested against gram-positive and gram-negative bacteria.
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- HY-145673
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Others
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Others
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Thiamphenicol glycinate, an alpha-amino acid ester, is a proagent of Thiamphenicol (HY-B0479) .
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- HY-131923
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Notch
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Cancer
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DAPM is a Notch pathway inhibitor with anticancer activity and antiproliferative effects. DAPM effectively inhibits tubular adenoma development by inhibiting cell proliferation and inducing the expression of Krüppel-like factor 4 (KLF4) and p21 in human colon cancer cells .
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- HY-152336
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Nucleoside Antimetabolite/Analog
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Others
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N1-(2-Methyl)propyl pseudouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-W037451
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Amino Acid Derivatives
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Others
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Methyl L-leucinate, methyl ester of L-leucine, is an alpha-amino acid ester. Methyl L-leucinate is a derivative of methyl ester and L-leucine, a class of compounds containing both amino and carboxyl groups in the molecule .
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- HY-109105
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XP-23829; PPC-06
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Others
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Inflammation/Immunology
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Tepilamide fumarate (XP-23829; PPC-06) is an oral fumaric acid ester, acts as a proagent of Monomethyl fumarate (HY-103252), and is used in the research of moderate to severe chronic plaque psoriasis .
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- HY-147152
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Others
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Others
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1-Myristoyl-3-chloropropanediol is a 3-monochloropropanediol (3-MCPD) fatty acid ester. 3-MPCD causes nephropathy and tubular hyperplasia and adenomas by chronic oral administration; also reduces fertility, or provokes infertility in rats and suppresses the immune function .
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- HY-W013214
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Endogenous Metabolite
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Others
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Ethyl arachidonate is a lipophilic esterified form of arachidonic acid (AA) and can be added into dietary regimens or fed to cultured cells as a source of exogenous arachidonate. Ethyl arachidonate is the main species of fatty acid ethyl esters (FAEE) in brain of alcohol-intoxicated subjects .
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- HY-N3944
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6β-acetoxy-5-epilimonin
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Others
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Others
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Glaucin B is a bitter limonoid isolated from the root bark of Evodia glauca .
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- HY-147079
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ARC 1779
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Integrin
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Cardiovascular Disease
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Egaptivon pegol (ARC1779) is an aptamer, which blocks binding of the von Willebrand Factor (VWF) to platelet GPIb receptors. Egaptivon pegol has anti-thrombotic efficacy.
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- HY-W009082
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Methyl docosanoate
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Others
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Others
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Methyl behenate (Methyl docosanoate) is a naturally fatty acid methyl ester isolated from the plant of Aspidopterys obcordata Lemsl .
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- HY-N12506
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Others
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Others
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Cimicifugic acid F is a hydroxycinnamic acid ester of piscidic acid isolated from the rhizomes of Cimicifuga racemosa.
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- HY-109561
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EYE001; NX1838
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VEGFR
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Metabolic Disease
Inflammation/Immunology
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Pegaptanib sodium is an RNA aptamer directed against vascular endothelial growth factor (VEGF)-165. Pegaptanib could be used for the study of neovascular age-related macular degeneration (AMD) .
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- HY-124422
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- HY-W011688
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(Z)-Methyl hexadec-9-enoate; Methyl cis-9-Hexadecenoate
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Others
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Others
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Methyl palmitoleate ((Z)-Methyl hexadec-9-enoate), a fatty acid methyl ester, is an analogue of Palmitoleate with cytoprotective and growth-promoting properties .
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- HY-N2073
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MCHR1 (GPR24)
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Cardiovascular Disease
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Ethyl linolenate is a fatty acid ethyl ester (FAEE). Ethyl linolenate plays an active role in inhibition of the cellular production on melanin with an IC50 of 70 μM. Anti-melanogenesis Effects .
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- HY-101197
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mAChR
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Others
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SM 21 maleate, 2-phenoxyalkanoic acid ester, binds to central muscarinic recrptor with affinity of 0.174 μM .
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- HY-N1030
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12α-acetoxy-12-deoxo-elliptone
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12-Deoxo-12α-acetoxyelliptone is a compound isolated from the roots of Derris oblonga .
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- HY-P4561
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Cathepsin
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Others
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H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH is a water-soluble polypeptide that can serve as a substrate for cathepsin D, pepsin and pepsinogen. H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH has potential applications in biochemical analysis .
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- HY-106084
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T-2525; RO 19-5247; Cefterame
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Bacterial
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Infection
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Cefteram (T-2525) is the free acid of Cefteram pivoxil (HY-106571), which is an orally active cephalosporin ester. Cefteram potently targets to the enteropathogenic Enterobacteriaceae and Vibrionaceae .
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- HY-163297
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Fungal
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Infection
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Antifungal agent 90 (Compound 7n) is an antifungal agent that inhibits ergosterol biosynthesis. Antifungal agent 90 showed excellent antifungal activity against Valsa mali and Botrytis cinerea with EC50 values respectively. 4.26 and 1.41 μg/mL .
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- HY-P4556
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Biochemical Assay Reagents
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Others
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H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe is a polypeptide that can be hydrolyzed by Rennin (HY-P2810). H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe is commonly used as a biochemical reaction reagent .
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- HY-117586
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- HY-W011297
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Arachidonic acid methyl ester
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Others
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Metabolic Disease
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Methyl arachidonate (Arachidonic acid methyl ester) is a fatty acid methyl ester resulting from the formal condensation of the carboxy group of arachidonic acid with methanol. Methyl arachidonate has activity of human blood serum metabolite .
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- HY-135087
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Biochemical Assay Reagents
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Others
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Caprylic/Capric Triglyceride is the triglycerides and esters prepared from fractionated vegetable oil sources and fatty acids from coconuts and palm kernel oils. Caprylic/Capric Triglyceride possesses excellent oxidation stability. Caprylic/Capric Triglyceride is used as a food additive and used in cosmetics .
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- HY-146981
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- HY-146984
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Glucosidase
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Inflammation/Immunology
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α-Glucosidase-IN-3 is an oleanolic acid (OA) oxime ester derivative against α-glucosidase (IC50=1.28 µM) and α-amylase (IC50=3.8 µM) .
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- HY-134124
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Reactive Oxygen Species
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Inflammation/Immunology
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Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .
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- HY-35028
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Amino Acid Derivatives
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Others
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Boc-Glu-Ofm is a peptide. Boc-Glu-Ofm has been used for the synthesis of ester insulin and cyclic peptide mixtures .
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- HY-P4146
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BI 456906
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GLP Receptor
GCGR
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Metabolic Disease
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Survodutide (BI 456906) is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .
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- HY-P4146A
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BI 456906 TFA
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GLP Receptor
GCGR
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Metabolic Disease
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Survodutide (BI 456906) TFA is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide TFA, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide TFA has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .
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- HY-118347
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Others
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Neurological Disease
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Aspartame acesulfame is a methyl ester of a dipeptide. Aspartame acesulfame can be used as a synthetic nonnutritive sweetener. Aspartame acesulfame is composed of phenylalanine (50%), aspartic acid (40%) and methanol (10%) .
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- HY-149832
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Proteasome
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Cancer
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Anticancer agent 114 is a potent and orally active dipeptide boronic acid ester proteasome inhibitor with an IC50 value of 2.2 nM. Anticancer agent 114 has antiproliferative activity against the RPMI-8226 cells. Anticancer agent 114 can be used in research of multiple myeloma .
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- HY-135357
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- HY-N8208
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Others
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Others
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Sibiricose A1is an oligosaccharide ester that can be found in Polygala tenuifolia .
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- HY-D1085
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Fluorescent Dye
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Others
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AMCA-X-SE is a coumarin derivative that generates fixed blue fluorescence and an NHS-activated ester that forms stable amide bonds with primary amine groups. It is used as a reactive dye for labeling amino groups of peptides, proteins, and oligonucleotides. Maximum excitation/emission wavelength: 354/442 nm .
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- HY-W016484
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- HY-P1108
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CFTR
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Others
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Astressin 2B is a potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist, with the IC50 values of 1.3 nM and > 500 nM for CRF2 and CRF1, respectively. Astressin 2B antagonizes CRF2-mediated inhibition of gastric emptying .
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- HY-P1108A
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CFTR
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Others
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Astressin 2B TFA is a potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist, with the IC50 values of 1.3 nM and > 500 nM for CRF2 and CRF1, respectively. Astressin 2B TFA antagonizes CRF2-mediated inhibition of gastric emptying .
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- HY-133027
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Tetradecyl nicotinate
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Others
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Cancer
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Myristyl nicotinate (Tetradecyl nicotinate) is an ester proagent and a lipophilic derivative of Nicotinic acid. Myristyl nicotinate is being developed for delivery of Nicotinic acid into the skin for prevention of actinic keratosis and its progression to skin cancer. Myristyl nicotinate shows to stimulate epidermal differentiation in photodamaged skin, increasing skin NAD content and strengthening the skin barrier .
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- HY-41344
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Antibiotic
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Infection
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Ganciclovir mono-O-acetate is a derivative of Ganciclovir. Ganciclovir, a nucleoside analogue, is an orally active antiviral agent with activity against CMV .
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- HY-129671
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5β-Hydroxyecdysterone
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Others
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Others
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Polypodine B is a natural ecdysone ester isolated from the bark of Dacrydium intermedium .
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- HY-D1730
-
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Fluorescent Dye
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Others
|
AF488 NHS ester is an amine specific fluorescence probe (Em=525 nm). AF488 NHS ester reacts with sulfhydryl groups and amines in aqueous and biological samples then change their chemical structure and fluorescence properties after derivatization .
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- HY-N12066
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Others
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Others
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Progenin III palmitate is a steroid glycoside ester isolated from Dioscorea cayenensis rhizomes .
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- HY-W017439
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Others
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Others
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Ethyl benzoate is ester from oil of the overground parts of Artemisia monosperma[1].
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- HY-125383
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- HY-W141825
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Fluorescent Dye
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Infection
Metabolic Disease
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N-Acetyl-DL-phenylalanine β-naphthyl ester is an aromatic amino acid ester, which functions as a chromogenic substrate for chymotrypsin and microbial serine proteases such as subtilisin .
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- HY-147304
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Bacterial
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Others
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BPH-1086 (compound 10) is an IspH inhibitor, IspH domain fused with ribosomal protein S1 (RPS1) can bind to mRNA or form part of the bacterial ribosome .
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Cat. No. |
Product Name |
Type |
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- HY-D1085
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Fluorescent Dyes/Probes
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AMCA-X-SE is a coumarin derivative that generates fixed blue fluorescence and an NHS-activated ester that forms stable amide bonds with primary amine groups. It is used as a reactive dye for labeling amino groups of peptides, proteins, and oligonucleotides. Maximum excitation/emission wavelength: 354/442 nm .
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- HY-W297715
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- HY-W141825
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Chromogenic Substrates
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N-Acetyl-DL-phenylalanine β-naphthyl ester is an aromatic amino acid ester, which functions as a chromogenic substrate for chymotrypsin and microbial serine proteases such as subtilisin .
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Cat. No. |
Product Name |
Type |
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- HY-A0025
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Biochemical Assay Reagents
|
(R)-2-acetoxy-2-phenylacetic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
- HY-W000978
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Isobutylboronic acid
|
Biochemical Assay Reagents
|
(2-Methylpropyl)boronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
- HY-135087
-
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Biochemical Assay Reagents
|
Caprylic/Capric Triglyceride is the triglycerides and esters prepared from fractionated vegetable oil sources and fatty acids from coconuts and palm kernel oils. Caprylic/Capric Triglyceride possesses excellent oxidation stability. Caprylic/Capric Triglyceride is used as a food additive and used in cosmetics .
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Cat. No. |
Product Name |
Target |
Research Area |
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- HY-W011324
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-
- HY-W012220
-
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Peptides
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Others
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(R)-4-Amino-2-((tert-butoxycarbonyl)amino)-4-oxobutanoic acid is an asparagine derivative .
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-
- HY-W007573
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-
- HY-P0041A
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-
- HY-W017069
-
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Amino Acid Derivatives
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Others
|
(S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(allyloxy)-4-oxobutanoic acid is an aspartic acid derivative .
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-
- HY-W002301
-
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Amino Acid Derivatives
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Others
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(2S)-4-(benzyloxy)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-4-oxobutanoic acid is an aspartic acid derivative .
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- HY-P4837
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Peptides
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Others
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Ac-Lys-D-Ala-D-lactic acid is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
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- HY-P10200
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Bacterial
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Infection
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CP7-FP13-2 is a peptide with antivirulence factor and antibacterial activity. CP7-FP13-2 inhibits the formation of Staphylococcus aureus biofilm and has good antibacterial efficacy in mice .
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- HY-P3462
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CGRP Receptor
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Metabolic Disease
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Cagrilintide is an investigational novel long-acting acylated amylin analogue, acts as nonselective amylin receptors (AMYR) and calcitonin G protein-coupled receptor (CTR) agonist. Cagrilintide induces significant weight loss and reduces food intake. Cagrilintide has the potential for the research of obesity .
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- HY-P3462A
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CGRP Receptor
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Metabolic Disease
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Cagrilintide acetate is a non-selective AMYR/CTR agonist and long-acting acylated amylase analogue. Cagrilintide acetate causes a reduction in food intake and significant weight loss in a dose-dependent manner. Cagrilintide acetate can be used in obesity studies .
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- HY-P5161A
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GCGR
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Metabolic Disease
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FC382K10W15 TFA is a glucagon analogue and GLP-1R/GCGR agonist. FC382K10W15 TFA can be used in type 2 diabetes research .
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- HY-P5161
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- HY-P3143
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PD-1/PD-L1
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Cancer
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BMSpep-57 is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC50 of 7.68 nM. BMSpep-57 binds to PD-L1 with Kds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 facilitates T cell function by in creasing IL-2 production in PBMCs .
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- HY-P3143A
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PD-1/PD-L1
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Cancer
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BMSpep-57 hydrochloride is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC50 of 7.68 nM. BMSpep-57 hydrochloride binds to PD-L1 with Kds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 hydrochloride facilitates T cell function by in creasing IL-2 production in PBMCs .
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- HY-P1162
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- HY-P4895
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Oxytocin Receptor
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Neurological Disease
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(d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin (OVT) is an oxytocin receptor antagonist. (d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin can be used for the research of neurological disease .
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- HY-131923
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Notch
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Cancer
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DAPM is a Notch pathway inhibitor with anticancer activity and antiproliferative effects. DAPM effectively inhibits tubular adenoma development by inhibiting cell proliferation and inducing the expression of Krüppel-like factor 4 (KLF4) and p21 in human colon cancer cells .
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- HY-W037451
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Amino Acid Derivatives
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Others
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Methyl L-leucinate, methyl ester of L-leucine, is an alpha-amino acid ester. Methyl L-leucinate is a derivative of methyl ester and L-leucine, a class of compounds containing both amino and carboxyl groups in the molecule .
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- HY-P3983
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Peptides
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Others
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[Cys(Bzl)84] CD (81-92) is an acidic peptide. [Cys(Bzl)84] CD (81-92) can be sequencing by negative ion postsource decay (PSD) spectra .
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- HY-P4561
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Cathepsin
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Others
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H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH is a water-soluble polypeptide that can serve as a substrate for cathepsin D, pepsin and pepsinogen. H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH has potential applications in biochemical analysis .
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- HY-P4556
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Biochemical Assay Reagents
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Others
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H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe is a polypeptide that can be hydrolyzed by Rennin (HY-P2810). H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe is commonly used as a biochemical reaction reagent .
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- HY-P4756
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Peptides
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Others
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N-(2-Carbamoyl-ethyl)-Val-Leu-anilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
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- HY-P4545
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Peptides
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Others
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Abz-Gly-p-nitro-Phe-Pro-OH is the fluorescent substrate angiotensin I converting enzyme (ACE-I) with 355 nm excitation and 405 nm emission wavelengths .
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- HY-134124
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Reactive Oxygen Species
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Inflammation/Immunology
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Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .
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- HY-P4755
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Peptides
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Others
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N-((RS)-2-Hydroxy-propyl)-Val-Leu-anilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
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- HY-P4725
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Peptides
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Others
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Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 is a fluorogenic substrate, that can be used for the fluorescence screening assay .
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- HY-35028
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Amino Acid Derivatives
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Others
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Boc-Glu-Ofm is a peptide. Boc-Glu-Ofm has been used for the synthesis of ester insulin and cyclic peptide mixtures .
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- HY-P4146
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BI 456906
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GLP Receptor
GCGR
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Metabolic Disease
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Survodutide (BI 456906) is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .
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- HY-P4146A
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BI 456906 TFA
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GLP Receptor
GCGR
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Metabolic Disease
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Survodutide (BI 456906) TFA is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide TFA, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide TFA has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .
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- HY-B0361
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SC-18862
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Peptides
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Neurological Disease
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Aspartame (SC-18862) is a methyl ester of a dipeptide. Aspartame can be used as a synthetic nonnutritive sweetener .
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- HY-148663
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Tripalmitoyl pentapeptide
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Peptides
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Inflammation/Immunology
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Mitogenic Pentapeptide (Tripalmitoyl pentapeptide) is an effective activator of B lymphocyte mitogen and polyclonal. Mitogen Pentapeptide is a synthetic N-terminal analog of E. coli outer membrane lipoproteins (cysteinyl-seryl-seryl-asparaginyl-alanine). Mitogenic Pentapeptide can be used for the study of immune adjuvants .
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- HY-P1108
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CFTR
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Others
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Astressin 2B is a potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist, with the IC50 values of 1.3 nM and > 500 nM for CRF2 and CRF1, respectively. Astressin 2B antagonizes CRF2-mediated inhibition of gastric emptying .
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- HY-P1108A
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CFTR
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Others
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Astressin 2B TFA is a potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist, with the IC50 values of 1.3 nM and > 500 nM for CRF2 and CRF1, respectively. Astressin 2B TFA antagonizes CRF2-mediated inhibition of gastric emptying .
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
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- HY-W009973S
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4-Anilino-4-oxobutanoic acid-d5 is the deuterium labeled 4-Anilino-4-oxobutanoic acid[1].
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-
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- HY-150628S
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2-Oxobutanoic acid- 13C,d1 sodium hydrate is the deuterium and 13C labeled 2-Oxobutanoic acid sodium hydrate.
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-
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- HY-W014504S1
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2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid-d7 is the deuterium labeled 2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid. 2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid is an endogenous metabolite.
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-
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- HY-W006057AS17
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3-Methyl-2-oxobutanoic acid- 13C2 is the 13C labeled Sodium 3-methyl-2-oxobutanoate[1]. Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli[2][3][4].
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- HY-14656S1
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Diltiazem-(acetoxy-d3) (hydrochloride) is the deuterium labeled Diltiazem hydrochloride. Diltiazem hydrochloride is a Ca2+ influx inhibitor (slow channel blocker or calcium antagonist)[1][2].
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