1. Protein Tyrosine Kinase/RTK
  2. c-Met/HGFR

2-Phospho-L-ascorbic acid trisodium salt (Synonyms: L-Ascorbic acid 2-phosphate trisodium salt; Sodium L-ascorbyl-2-phosphate)

Cat. No.: HY-107837 Purity: 99.36%
Handling Instructions

2-Phospho-L-ascorbic acid trisodium salt acts as an antioxidant and a stimulator of hepatocyte growth factor (HGF) production.

For research use only. We do not sell to patients.

2-Phospho-L-ascorbic acid trisodium salt Chemical Structure

2-Phospho-L-ascorbic acid trisodium salt Chemical Structure

CAS No. : 66170-10-3

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10 mM * 1 mL in Water USD 55 In-stock
Estimated Time of Arrival: December 31
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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

2-Phospho-L-ascorbic acid trisodium salt acts as an antioxidant and a stimulator of hepatocyte growth factor (HGF) production.

In Vitro

2-Phospho-L-ascorbic acid (Asc 2-P) acts as an antioxidant and a stimulator of hepatocyte growth factor (HGF) production. 2-Phospho-L-ascorbic acid is a stable derivative of L-ascorbic acid (AA) and possesses similar biological properties as AA. AA and Asc-2P regulate a number of biological processes[1]. When 2-Phospho-L-ascorbic acid is added together with DHT, DHT-induced DKK-1 mRNA expression in DPCs is significantly attenuated. It is also found that DKK-1 promoter activity is increased by DHT treatmen. When 2-Phospho-L-ascorbic acid is added together with DHT, DHT-induced activation of luciferase activity is significantly repressed[2].

Solvent & Solubility
In Vitro: 

H2O : 150 mg/mL (465.77 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1051 mL 15.5255 mL 31.0511 mL
5 mM 0.6210 mL 3.1051 mL 6.2102 mL
10 mM 0.3105 mL 1.5526 mL 3.1051 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 0.6 mg/mL (1.86 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 0.6 mg/mL (1.86 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 0.6 mg/mL (1.86 mM); Clear solution

References
Molecular Weight

322.05

Formula

C₆H₆Na₃O₉P

CAS No.

66170-10-3

SMILES

O[[email protected]@H](CO)[[email protected]@H](O1)C(O[Na])=C(OP(O[Na])(O[Na])=O)C1=O

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
2-Phospho-L-ascorbic acid trisodium salt
Cat. No.:
HY-107837
Quantity:

2-Phospho-L-ascorbic acid trisodium salt

Cat. No.: HY-107837