1. Metabolic Enzyme/Protease
  2. Dipeptidyl Peptidase
  3. DPP-IV-IN-1

DPP-IV-IN-1 

Cat. No.: HY-U00346 Purity: 98.79%
Handling Instructions

DPP-IV-IN-1 is a potent inhibitor of dipeptidyl peptidase IV (DPP-IV), a highly specific serine protease, with an IC50 of 4.6 nM.

For research use only. We do not sell to patients.

DPP-IV-IN-1 Chemical Structure

DPP-IV-IN-1 Chemical Structure

CAS No. : 625110-37-4

Size Price Stock Quantity
5 mg USD 1750 In-stock
Estimated Time of Arrival: December 31
10 mg USD 2800 In-stock
Estimated Time of Arrival: December 31
25 mg USD 5600 In-stock
Estimated Time of Arrival: December 31
50 mg USD 9000 In-stock
Estimated Time of Arrival: December 31
100 mg USD 14500 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Description

DPP-IV-IN-1 is a potent inhibitor of dipeptidyl peptidase IV (DPP-IV), a highly specific serine protease, with an IC50 of 4.6 nM.

In Vivo

DPP-IV-IN-1 (0.1 and 0.3 mg/kg, p.o.) reduces the increase in plasma glucose beginning 30 min after glucose loading, and significantly suppresses hyperglycemia at the dose of 0.3 mg/kg in a rat model of obesity and impaired glucose tolerance. The effect is based on its inhibitory effect on plasma DPP-IV activity[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

243.28

Formula

C11H18FN3O2

CAS No.
SMILES

N#C[[email protected]]1N(C(CNC(C)(C)CO)=O)C[[email protected]@H](F)C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (513.81 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.1105 mL 20.5525 mL 41.1049 mL
5 mM 0.8221 mL 4.1105 mL 8.2210 mL
10 mM 0.4110 mL 2.0552 mL 4.1105 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Product Name:
DPP-IV-IN-1
Cat. No.:
HY-U00346
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