1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Actinine-d9 chloride

Actinine-d9 chloride  (Synonyms: γ-Butyrobetaine-d9 hydrochloride; Deoxycarnitine-d9 hydrochloride)

Cat. No.: HY-113270AS Purity: ≥98.0%
COA Handling Instructions

Actinine-d9 chloride is the deuterium labeled Actinine chloride. Actinine chloride is angiopathic substance produced as an intermediary metabolite by gut microbiota that feed on carnitine in dietary red meat[1][2].

For research use only. We do not sell to patients.

Actinine-d<sub>9</sub> chloride Chemical Structure

Actinine-d9 chloride Chemical Structure

CAS No. : 85806-17-3

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5 mg USD 240 In-stock
10 mg USD 390 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Actinine-d9 chloride is the deuterium labeled Actinine chloride. Actinine chloride is angiopathic substance produced as an intermediary metabolite by gut microbiota that feed on carnitine in dietary red meat[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

190.72

Formula

C7H7D9ClNO2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[2H]C([N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])CCCC(O)=O)([2H])[2H].[Cl-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (131.08 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.2433 mL 26.2164 mL 52.4329 mL
5 mM 1.0487 mL 5.2433 mL 10.4866 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.2433 mL 26.2164 mL 52.4329 mL 131.0822 mL
5 mM 1.0487 mL 5.2433 mL 10.4866 mL 26.2164 mL
10 mM 0.5243 mL 2.6216 mL 5.2433 mL 13.1082 mL
15 mM 0.3496 mL 1.7478 mL 3.4955 mL 8.7388 mL
20 mM 0.2622 mL 1.3108 mL 2.6216 mL 6.5541 mL
25 mM 0.2097 mL 1.0487 mL 2.0973 mL 5.2433 mL
30 mM 0.1748 mL 0.8739 mL 1.7478 mL 4.3694 mL
40 mM 0.1311 mL 0.6554 mL 1.3108 mL 3.2771 mL
50 mM 0.1049 mL 0.5243 mL 1.0487 mL 2.6216 mL
60 mM 0.0874 mL 0.4369 mL 0.8739 mL 2.1847 mL
80 mM 0.0655 mL 0.3277 mL 0.6554 mL 1.6385 mL
100 mM 0.0524 mL 0.2622 mL 0.5243 mL 1.3108 mL
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Actinine-d9 chloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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