1. Cell Cycle/DNA Damage
  2. Checkpoint Kinase (Chk)
  3. CHK1 inhibitor

CHK1 inhibitor 

Cat. No.: HY-104022
Handling Instructions

CHK1 inhibitor is an inhibitor of CHK1.

For research use only. We do not sell to patients.

CHK1 inhibitor Chemical Structure

CHK1 inhibitor Chemical Structure

CAS No. : 2097938-64-0

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Description

CHK1 inhibitor is an inhibitor of CHK1.

IC50 & Target

CHK1

Clinical Trial
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 150 mg/mL (397.58 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6506 mL 13.2528 mL 26.5055 mL
5 mM 0.5301 mL 2.6506 mL 5.3011 mL
10 mM 0.2651 mL 1.3253 mL 2.6506 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (6.63 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (6.63 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (6.63 mM); Clear solution

*All of the co-solvents are provided by MCE.
Molecular Weight

377.28

Formula

C₁₇H₂₁BrN₄O

CAS No.

2097938-64-0

SMILES

O=C(C1CC1)NC2=CNC3=C2C(N4C[[email protected]](N)CCC4)=C(Br)C=C3

Shipping

Room temperature in continental US; may vary elsewhere

  • 不定价,药明ref丁佳丽要求上线20180706Oncol Res. 2011;19(7):349-63.;竞价CAS
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
CHK1 inhibitor
Cat. No.:
HY-104022
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CHK1 inhibitor

Cat. No.: HY-104022