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Product Name: | 7-xylosyltaxol | |
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CAS No.: | 90332-66-4 | |
Cat. No.: | HY-77574 | |
MWt: | 986.02 | |
Formula: | C52H59NO18 | |
Purity : | >98% | |
Solubility: | 10 mM in DMSO | |
Mechanisms: | Target: Cancer | |
Biological Activity: | ||
7-xylosyltaxol(Taxol-7-xyloside) is a taxol (Paclitaxel) derivative; Paclitaxel binds to tubulin and inhibits the disassembly of microtubules. IC50 Value: Target: Microtubule/Tubulin Paclitaxel is a compound extracted from the Pacific yew tree with antineoplastic activity. Paclitaxel also induces apoptosis by binding to and blocking the function of the apoptosis inhibitor protein Bcl-2 (B-cell Leukemia 2). Paclitaxel inhibits DNA synthesis and stimulates the release of tumor necrosis factor-α. Paclitaxel induces apoptosis in murine mammary carcinoma MCA-4 and ovarian carcinoma OCA-1 tumors. |
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