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Cabazitaxel Data Sheet

Product Name: Cabazitaxel
CAS No.: 183133-96-2
Cat. No.: HY-15459
MWt: 835.93
Formula: C45H57NO14
Purity : >98%
Solubility: DMSO : ≥ 100 mg/mL (119.63 mM)
Mechanisms: Target: Cancer
Biological Activity:
Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity. In Vitro: The cytotoxicity of cabazitaxel (100 μg/mL) on 4T1 cells without irradiation is 70.8%. Cabazitaxel (100 μg/mL) exhibits a concentration-dependent antiproliferation effect, with the antiproliferative activity of 56.2%[1]. In Vivo: Cabazitaxel (10 mg/kg, i.v.) has certain toxicity to liver and kidney but it can be avoided by integrated into Ans. The body weights of mice treated with AN-ICG-CBX and AN-CBX have a slightly decrease, while body weights of the free CBX group significantly decrease compared to the control group[1].

Caution: Not fully tested. For research purposes only

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