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Podofilox Data Sheet

Product Name: Podofilox
CAS No.: 518-28-5
Cat. No.: HY-15552
MWt: 414.41
Formula: C22H22O8
Purity : >98%
Solubility: DMSO : ≥ 100 mg/mL (241.31 mM)
Mechanisms: Target: Cancer
Biological Activity:
Podofilox (Podophyllotoxin) is a potent inhibitor of microtubule assembly and DNA topoisomerase II. IC50 & Target: Topoisomerase II; Microtubule/Tubulin In Vitro: Podophyllotoxin, a kind of non-alkaloid toxin lignan extracted from the roots and rhizomes of Podophyllum plant, has been shown to inhibit the growth of various carcinoma cells. Podophyllotoxin is a natural product that inhibits the polymerization of tubulin and has served as a prototype for the development of diverse antitumor agents in clinical use.

Caution: Not fully tested. For research purposes only

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