1. GPCR/G Protein
    Autophagy
  2. Cannabinoid Receptor
    Autophagy

JWH-133 

Cat. No.: HY-15854 Purity: >95.0%
Data Sheet SDS Handling Instructions

JWH 133 is a potent CB2 selective agonist with Ki of 3.4 nM, 200-fold selective over CB1 receptors.

For research use only. We do not sell to patients.
JWH-133 Chemical Structure

JWH-133 Chemical Structure

CAS No. : 259869-55-1

Size Price Stock Quantity
10 mM * 1 mL in DMSO $121 In-stock
5 mg $110 In-stock
10 mg $190 In-stock
25 mg $400 In-stock
50 mg $720 In-stock
100 mg   Get quote  
200 mg   Get quote  

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Customer Review

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

JWH 133 is a potent CB2 selective agonist with Ki of 3.4 nM, 200-fold selective over CB1 receptors. target: CB2 In vitro: JWH-133 inhibits IL-12p40 production and enhances IL-10 release by activated macrophages through a CB2 receptor-mediated pathway. [1] , a widely used experimental in vitro model to study mechanisms of toxicity and protection in nigral dopaminergic neurons. JWH-133 (10-40 μM) induced a concentration-dependent decrease of SH-SY5Y cell viability and proliferation rate. [2] In vivo: The reference for animal injection is 1.5 mg/kg i.v.[3]

References
Molecular Weight

312.49

Formula

C₂₂H₃₂O

CAS No.

259869-55-1

Storage
Pure form -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
JWH-133
Cat. No.:
HY-15854
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