1. GPCR/G Protein
    Neuronal Signaling
  2. Adrenergic Receptor
  3. L-Epinephrine Bitartrate

L-Epinephrine Bitartrate (Synonyms: (-)-Epinephrine (+)-bitartrate salt; L-Adrenaline (+)-bitartrate salt)

Cat. No.: HY-B0447A Purity: >99.0%
Handling Instructions

L-Epinephrine bitartrate is an α-adrenergic and β-adrenergic receptor agonist. L-Epinephrine is a hormone secreted by the medulla of the adrenal glands.

For research use only. We do not sell to patients.

L-Epinephrine Bitartrate Chemical Structure

L-Epinephrine Bitartrate Chemical Structure

CAS No. : 51-42-3

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10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
500 mg USD 50 In-stock
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1 g USD 60 In-stock
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5 g USD 132 In-stock
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Customer Review

Based on 4 publication(s) in Google Scholar

Other Forms of L-Epinephrine Bitartrate:

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Description

L-Epinephrine bitartrate is an α-adrenergic and β-adrenergic receptor agonist. L-Epinephrine is a hormone secreted by the medulla of the adrenal glands.

In Vivo

A 25 microliter volume of a 1-% L-epinephrine borate solution applied on the cornea of one eye in 12 monkeys reduces blood flow through the iris and the ciliary body by 59% and 20%, respectively, compared to the untreated control eyes[1]. Epinephrine is a direct-acting sympathomimetic α-adrenergic and β-adrenergic agonist with cyclic adenosine monophosphate-mediated, complex, bidirectional pharmacologic effects on many target organs[2]. In young adult rats, endogenous release of epinephrine facilitates stable memory formation for temporally associated events. Epinephrine enhances memory in young adult rats, in part, by increasing blood glucose levels needed to modulate memory[3]. Epinephrine is the primary drug administered during cardiopulmonary resuscitation (CPR) to reverse cardiac arrest. Epinephrine increases arterial blood pressure and coronary perfusion during CPR via alpha-1-adrenoceptor agonist effects[4].

Clinical Trial
Molecular Weight

333.29

Formula

C₁₃H₁₉NO₉

CAS No.

51-42-3

SMILES

O[[email protected]](C1=CC(O)=C(O)C=C1)CNC.O[[email protected]@H](C(O)=O)[[email protected]@H](O)C(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (300.04 mM; adjust pH to 2 with HCl)

DMSO : 50 mg/mL (150.02 mM; Need ultrasonic)

H2O : ≥ 50 mg/mL (150.02 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0004 mL 15.0019 mL 30.0039 mL
5 mM 0.6001 mL 3.0004 mL 6.0008 mL
10 mM 0.3000 mL 1.5002 mL 3.0004 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (7.50 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (7.50 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (7.50 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Keywords:

L-Epinephrine Bitartrate(-)-Epinephrine (+)-bitartrateL-Adrenaline (+)-bitartrateAdrenergic ReceptorBeta ReceptorInhibitorinhibitorinhibit

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L-Epinephrine Bitartrate
Cat. No.:
HY-B0447A
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