1. Metabolic Enzyme/Protease
  2. Indoleamine 2,3-Dioxygenase (IDO)
  3. LY-3381916

LY-3381916 

Cat. No.: HY-111540
Handling Instructions

LY-3381916 is a potent, selective and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1.

For research use only. We do not sell to patients.

LY-3381916 Chemical Structure

LY-3381916 Chemical Structure

CAS No. : 2166616-75-5

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  • References

Description

LY-3381916 is a potent, selective and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1[1].

IC50 & Target[1]

IDO1

 

In Vitro

LY-3381916 (up to 100 µM) shows no obvious agonism of aryl hydrocarbon receptor (AHR)[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

396.45

Formula

C₂₃H₂₅FN₂O₃

CAS No.

2166616-75-5

SMILES

FC1=CC=C(C(N[[email protected]](C)C2=CC=C(N(C(C3CCOCC3)=O)CC4)C4=C2)=O)C=C1

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
LY-3381916
Cat. No.:
HY-111540
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LY-3381916

Cat. No.: HY-111540