1. Cell Cycle/DNA Damage
    Epigenetics
  2. Aurora Kinase
  3. Aurora B inhibitor 1

Aurora B inhibitor 1 

Cat. No.: HY-U00304
Handling Instructions

Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor extracted from patent WO2007059299A1, compound 1-3, has a Ki value of <0.010 uM.

For research use only. We do not sell to patients.

Aurora B inhibitor 1 Chemical Structure

Aurora B inhibitor 1 Chemical Structure

CAS No. : 937276-52-3

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Description

Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor extracted from patent WO2007059299A1, compound 1-3, has a Ki value of <0.010 uM.

IC50 & Target[1]

Aurora B

0.01 μM (Ki)

In Vitro

Aurora B inhibitor 1 also inhibits JAK3 and JAK2 with Kis of <0.25 μM and <0.10 μM, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

529.97

Formula

C₂₅H₂₆ClF₂N₇O₂

CAS No.
SMILES

FC1(C2CC2)CN(C3=NC(O[[email protected]@H]4CN(C(C5=C(C=CC(Cl)=C5)F)=O)CC4)=NC(NC6=NNC(C)=C6)=C3)C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

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Aurora B inhibitor 1
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HY-U00304
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