1. GPCR/G Protein
  2. GNRH Receptor

Nafarelin 

Cat. No.: HY-P0057 Purity: 98.99%
Handling Instructions

Nafarelin is a gonadotropin-releasing hormone (GnRH) agonist that stimulates secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Sequence: {Glp}-His-Trp-Ser-Tyr-{2-Naph-Ala}-Leu-Arg-Pro-Gly-NH2.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Nafarelin Chemical Structure

Nafarelin Chemical Structure

CAS No. : 76932-56-4

Size Price Stock Quantity
10 mM * 1 mL in Water USD 175 In-stock
Estimated Time of Arrival: December 31
1 mg USD 60 In-stock
Estimated Time of Arrival: December 31
5 mg USD 84 In-stock
Estimated Time of Arrival: December 31
10 mg USD 120 In-stock
Estimated Time of Arrival: December 31
25 mg USD 192 In-stock
Estimated Time of Arrival: December 31
50 mg USD 240 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Nafarelin is a gonadotropin-releasing hormone (GnRH) agonist that stimulates secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Sequence: {Glp}-His-Trp-Ser-Tyr-{2-Naph-Ala}-Leu-Arg-Pro-Gly-NH2.

IC50 & Target

GnRH[1].

In Vitro

Nafarelin is a gonadotropin-releasing hormone (GnRH) agonist that stimulates secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH)[1]. Nafarelin is used effectively in in vitro fertilisation programmes. Nafarelin is readily and rapidly absorbed following intranasal delivery, and is protected to some extent from enzymatic degradation GnRH[2].

Clinical Trial
Solvent & Solubility
In Vitro: 

H2O : ≥ 330 mg/mL (249.53 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.7562 mL 3.7808 mL 7.5616 mL
5 mM 0.1512 mL 0.7562 mL 1.5123 mL
10 mM 0.0756 mL 0.3781 mL 0.7562 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

1322.47

Formula

C₆₆H₈₃N₁₇O₁₃

CAS No.

76932-56-4

Storage
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Nafarelin
Cat. No.:
HY-P0057
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Nafarelin

Cat. No.: HY-P0057