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  2. Terpenoids and Glycosides

Terpenoids and Glycosides

The terpenoids are a large and diverse class of naturally occurring organic chemicals, derived from five-carbon isoprene units assembled and modified in thousands of ways. Most are multicyclic structures that differ from one another not only in functional groups but also in their basic carbon skeletons. They can be classified according to the number of isoprene units used: Hemiterpenoids, Monoterpenoids, Sesquiterpenoids, Diterpenoids, Sesterterpenoids, Triterpenoids, Tetraterpenoids. These lipids can be found in all classes of living things, and are the largest group of natural products. Plant terpenoids are used extensively for their aromatic qualities and play a role in traditional herbal remedies. Terpenoids contribute to the scent of eucalyptus, the flavors of cinnamon, cloves, and ginger, the yellow color in sunflowers, and the red color in tomatoes.

Terpenoids and Glycosides (182):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-15371
    Forskolin 66575-29-9 98.52%
    Forskolin is a potent adenylate cyclase activator, with IC50 and EC50 of 41 nM and 0.5 μM for type I adenylyl cyclase, respectively.
    Forskolin
  • HY-32735
    Triptolide 38748-32-2 99.83%
    Triptolide is a diterpenoid triepoxide extracted from the root of Tripterygium wilfordii with immunosuppressive, anti-inflammatory and antiproliferative effects. Triptolide is a NF-κB activation inhibitor.
    Triptolide
  • HY-13067
    Celastrol 34157-83-0 99.90%
    Celastrol is a proteasome inhibitor which potently and preferentially inhibits the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 μM.
    Celastrol
  • HY-17389
    Genipin 6902-77-8 99.40%
    Genipin is a natural water soluble crosslinking reagent.
    Genipin
  • HY-N0176
    Dihydroartemisinin 71939-50-9 >99.0%
    Dihydroartemisinin is a potent anti-malaria agent.
    Dihydroartemisinin
  • HY-N0431
    Astragaloside IV 84687-43-4 99.15%
    Astragaloside IV, an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells.
    Astragaloside IV
  • HY-B0094
    Artemisinin 63968-64-9 >98.0%
    Artemisinin is an anti-malarial drug isolated from the aerial parts of Artemisia annua L. plants.
    Artemisinin
  • HY-N0141
    Parthenolide 20554-84-1 99.13%
    Parthenolide is an NF-κB inhibitor, reduces histone deacetylase 1 (HDAC-1) and DNA methyltransferase 1 independent of NF-κB inhibition.
    Parthenolide
  • HY-N0184
    Glycyrrhizic acid 1405-86-3 >98.0%
    Glycyrrhizic acid is a triterpenoid saponinl, acting as a direct HMGB1 antagonist, with anti-tumor, anti-diabetic activities.
    Glycyrrhizic acid
  • HY-101391
    Picrotoxin 124-87-8 >98.0%
    Picrotoxin is a noncompetitive antagonist of GABAA receptor.
    Picrotoxin
  • HY-N0904
    Ginsenoside C-K 39262-14-1 >98.0%
    Ginsenoside C-K, a bacterial metabolite of G-Rb1, exhibits anti-inflammatory effects by reducing iNOS and COX-2. Ginsenoside C-K exhibits an inhibition against the activity of CYP2C9 and CYP2A6 in human liver microsomes with IC50s of 32.0±3.6 μM and 63.6±4.2 μM, respectively.
    Ginsenoside C-K
  • HY-N0191
    Andrographolide 5508-58-7
    Andrographolide is a NF-κB inhibitor, which inhibits NF-κB activation through covalent modification of a cysteine residue on p50 in endothelial cells without affecting IκBα degradation or p50/p65 nuclear translocation.
    Andrographolide
  • HY-10529
    Betulinic acid 472-15-1 98.58%
    Betulinic acid is a natural pentacyclic triterpenoid, acts as a eukaryotic topoisomerase I inhibitor, with an IC50 of 5 μM, and possesses anti-HIV, anti-malarial, anti-inflammatory and anti-tumor properties.
    Betulinic acid
  • HY-N0603
    Ginsenoside Rg3 14197-60-5 >98.0%
    Ginsenoside Rg3 is the main component of Red ginseng. Ginsenoside Rg3 inhibits Na+ and hKv1.4 channel with IC50s of 32.2±4.5 and 32.6±2.2 μM, respectively. Ginsenoside Rg3 also inhibits levels, NF-κB activity, and COX-2 expression.
    Ginsenoside Rg3
  • HY-B0719
    Ingenol Mebutate 75567-37-2 98.74%
    Ingenol Mebutate is an active ingredient in Euphorbia peplus, acts as a potent PKC modulator, with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM for PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε, respectively, and has antiinflammatory and antitumor activity.
    Ingenol Mebutate
  • HY-N1405
    Cucurbitacin I 2222-07-3 >98.0%
    Cucurbitacin I is a natural selective inhibitor of JAK2/STAT3, with potent anti-cancer activity.
    Cucurbitacin I
  • HY-N0293
    Paeoniflorin 23180-57-6 >98.0%
    Paeoniflorin is a herbal constituent extracted from the root of Paeonia albiflora Pall.
    Paeoniflorin
  • HY-N0529
    Rosmarinic acid 20283-92-5 99.06%
    Rosmarinic acid (RA) is a widespread phenolic ester compound in the plants. Rosmarinic acid inhibits MAO-A, MAO-B and COMT enzymes with IC50s of 50.1, 184.6 and 26.7 μM, respectively.
    Rosmarinic acid
  • HY-N0009
    Geniposide 24512-63-8 99.52%
    Geniposide is an iridoid glucoside extracted from Gardenia jasminoides Ellis fruits; exhibits a varity of biological activities such as anti-diabetic, antioxidative, antiproliferative and neuroprotective activities.
    Geniposide
  • HY-N0416
    Cucurbitacin B 6199-67-3 99.68%
    Cucurbitacin B belongs to a class of highly oxidized tetracyclic triterpenoids; could repress cancer cell progression.
    Cucurbitacin B