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  2. Terpenoids and Glycosides

Terpenoids and Glycosides

The terpenoids are a large and diverse class of naturally occurring organic chemicals, derived from five-carbon isoprene units assembled and modified in thousands of ways. Most are multicyclic structures that differ from one another not only in functional groups but also in their basic carbon skeletons. They can be classified according to the number of isoprene units used: Hemiterpenoids, Monoterpenoids, Sesquiterpenoids, Diterpenoids, Sesterterpenoids, Triterpenoids, Tetraterpenoids. These lipids can be found in all classes of living things, and are the largest group of natural products. Plant terpenoids are used extensively for their aromatic qualities and play a role in traditional herbal remedies. Terpenoids contribute to the scent of eucalyptus, the flavors of cinnamon, cloves, and ginger, the yellow color in sunflowers, and the red color in tomatoes.

Terpenoids and Glycosides (174):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-15371
    Forskolin 66575-29-9 98.52%
    Forskolin is a potent adenylate cyclase activator, with binding (IC50=41 nM) to and activation (EC50=0.5 μM) of type I adenylyl cyclase.
    Forskolin
  • HY-32735
    Triptolide 38748-32-2 99.83%
    Triptolide is an inhibitor of heat shock factor (HSF1), inhibits HSP90-CDC37 binding and induces acetylation of HSP90, and also inhibits MDM2 expression in a dose-dependent manner with IC50 values range from 47 to 73 nM.
    Triptolide
  • HY-13067
    Celastrol 34157-83-0 99.90%
    Celastrol is a proteasome inhibitor, potently and preferentially inhibits the chymotrypsin-like activity of a purified 20S proteasome (IC50=2.5 μM).
    Celastrol
  • HY-17389
    Genipin 6902-77-8 99.42%
    Genipin is a cell permeable inhibitor of uncoupling protein 2 (UCP2).
    Genipin
  • HY-N0176
    Dihydroartemisinin 71939-50-9 >99.0%
    Dihydroartemisinin inhibits NF-κB activity by blocking RelA/p65 translocation to the nucleus. Dihydroartemisinin activates autophagy induction in tumor cells.
    Dihydroartemisinin
  • HY-B0094
    Artemisinin 63968-64-9 >98.0%
    Artemisinin, a natural product that is widely used as an anti-malarial drug, is an inhibitor of HCV subgenomic replicon replication.
    Artemisinin
  • HY-N0141
    Parthenolide 20554-84-1 99.13%
    Parthenolide is an NF-κB inhibitor, reduces histone deacetylase 1 (HDAC-1) and DNA methyltransferase 1 independent of NF-κB inhibition.
    Parthenolide
  • HY-N0603
    Ginsenoside Rg3 14197-60-5 >98.0%
    Ginsenoside Rg3 is the main component of Red ginseng. Ginsenoside Rg3 inhibits Na+ and hKv1.4 channel with IC50s of 32.2±4.5 and 32.6±2.2 μM, respectively. Ginsenoside Rg3 also inhibits levels, NF-κB activity, and COX-2 expression.
    Ginsenoside Rg3
  • HY-N0904
    Ginsenoside C-K 39262-14-1 98.06%
    Ginsenoside C-K, a bacterial metabolite of G-Rb1, exhibits anti-inflammatory effects by reducing iNOS and COX-2. Ginsenoside C-K exhibits an inhibition against the activity of CYP2C9 and CYP2A6 in human liver microsomes with IC50s of 32.0±3.6 μM and 63.6±4.2 μM, respectively.
    Ginsenoside C-K
  • HY-N0431
    Astragaloside IV 84687-43-4 99.15%
    Astragaloside IV, an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells.
    Astragaloside IV
  • HY-N0191
    Andrographolide 5508-58-7
    Andrographolide is a NF-κB inhibitor, which inhibits NF-κB activation through covalent modification of a cysteine residue on p50 in endothelial cells without affecting IκBα degradation or p50/p65 nuclear translocation.
    Andrographolide
  • HY-N0009
    Geniposide 24512-63-8 99.52%
    Geniposide is an iridoid glucoside extracted from Gardenia jasminoides Ellis fruits; exhibits a varity of biological activities such as anti-diabetic, antioxidative, antiproliferative and neuroprotective activities.
    Geniposide
  • HY-N0293
    Paeoniflorin 23180-57-6 >98.0%
    Paeoniflorin is a herbal constituent extracted from the root of Paeonia albiflora Pall.
    Paeoniflorin
  • HY-10529
    Betulinic acid 472-15-1 98.58%
    Betulinic acid is a natural pentacyclic triterpenoid, acts as a eukaryotic topoisomerase I inhibitor, with an IC50 of 5 μM, and possesses anti-HIV, anti-malarial, anti-inflammatory and anti-tumor properties.
    Betulinic acid
  • HY-B0719
    Ingenol Mebutate 75567-37-2 98.74%
    Ingenol Mebutate (PEP 005) is a substance found in the sap of the plant Euphorbia peplus and an inducer of cell death.
    Ingenol Mebutate
  • HY-N0184
    Glycyrrhizic acid 1405-86-3 >98.0%
    Glycyrrhizic acid is a triterpenoid saponinl, extracted from the licorice root, with anti-tumor, anti-diabetic activities.
    Glycyrrhizic acid
  • HY-N2312
    Mogrol 88930-15-8 98.06%
    Mogrol is a biometabolite of mogrosides, and acts via inhibition of the ERK1/2 and STAT3 pathways, or reducing CREB activation and activating AMPK signaling.
    Mogrol
  • HY-N0039
    Ginsenoside Rb1 41753-43-9 >98.0%
    Ginsenoside Rb1, a main constituent of the root of Panax ginseng, inhibits Na+, K+-ATPase activity with an IC50 of 6.3±1.0 μM. Ginsenoside also inhibits IRAK-1 activation and phosphorylation of NF-κB p65 .
    Ginsenoside Rb1
  • HY-N0668
    Rubusoside 64849-39-4 98.58%
    Rubusoside is a natural sweetener and a solubilizing agent with antiangiogenic and antiallergic properties.
    Rubusoside
  • HY-N0045
    Ginsenoside Rg1 22427-39-0 >98.0%
    Ginsenoside Rg1 is one of the major active components of ginseng. Ginsenoside Rg1 displays promising effects by reducing cerebral levels. Ginsenoside Rg1 also reduces NF-κB nuclear translocation.
    Ginsenoside Rg1